Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)
文献类型：期刊论文
| 作者 | Taechowisan, Thongchai; Tuntiwachwuttikul, Pittaya; Lu, Chunhua; Shen, Yuemao; Lumyong, Saisamorn; Taylor, Walter C. |
| 刊名 | IMMUNOLOGICAL INVESTIGATIONS
 |
| 出版日期 | 2007 |
| 卷号 | 36期号:2页码:203-211 |
| 关键词 | 4-arylcoumarins anti-inflammatory activity endophytic Streptomyces murine macrophage RAW 264.7 cells |
| 英文摘要 | This research was undertaken to test the in vitro anti-inflammatory action of 5,7,4'-trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin produced by Streptomyces aureofaciens CMUAc130. The effects of the two coumarins were investigated on the formation of NO, PGE(2), and TNF-alpha and also on inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cells. The data obtained were consistent with the modulation of iNOS enzyme expression. A similar effect was also observed when LPS-induced PGE(2) release and COX-2 expression were tested. The inhibitory effects were shown in concentration-dependent manners. The 5,7,4'-Trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin also mildly but significantly reduced the formation of TNF-alpha. |
| 类目[WOS] | Immunology |
| 研究领域[WOS] | Immunology |
| 关键词[WOS] | NITRIC-OXIDE GENERATION ; ANTIFUNGAL ACTIVITY ; LIPOPOLYSACCHARIDE ; COUMARINS ; INFLAMMATION ; ROOTS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000245244700007 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/24813]  |
| 专题 | 昆明植物研究所_离退休 |
| 作者单位 | 1.Silpakorn Univ, Dept Microbiol, Fac Sci, Pathom 73000, Thailand 2.Silpakorn Univ, Dept Chem, Fac Sci, Pathom 73000, Thailand 3.Xiamen Univ, Sch Life Sci, Xiamen, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, Kunming, Peoples R China 5.Chiang Mai Univ, Fac Sci, Dept Biol, Chiang Mai 50000, Thailand 6.Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia |
| 推荐引用方式 GB/T 7714 | Taechowisan, Thongchai,Tuntiwachwuttikul, Pittaya,Lu, Chunhua,et al. Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)[J]. IMMUNOLOGICAL INVESTIGATIONS,2007,36(2):203-211. |
| APA | Taechowisan, Thongchai,Tuntiwachwuttikul, Pittaya,Lu, Chunhua,Shen, Yuemao,Lumyong, Saisamorn,&Taylor, Walter C..(2007).Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009).IMMUNOLOGICAL INVESTIGATIONS,36(2),203-211. |
| MLA | Taechowisan, Thongchai,et al."Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells (Retracted article. See vol. 38, pg. 869, 2009)".IMMUNOLOGICAL INVESTIGATIONS 36.2(2007):203-211. |
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来源：昆明植物研究所
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