Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels
文献类型：期刊论文
| 作者 | Zhu, Yingmin1; Lu, Yungang1,2; Qu, Chunrong3; Miller, Melissa4,5; Tian, Jinbin1; Thakur, Dhananjay P.1; Zhu, Jinmei3; Deng, Zixin3; Hu, Xianming2; Wu, Meng4,5 |
| 刊名 | BRITISH JOURNAL OF PHARMACOLOGY
 |
| 出版日期 | 2015-07-01 |
| 卷号 | 172期号:14页码:3495-3509 |
| 英文摘要 | Background and PurposeTransient receptor potential canonical (TRPC) channels play important roles in a broad array of physiological functions and are involved in various diseases. However, due to a lack of potent subtype-specific inhibitors the exact roles of TRPC channels in physiological and pathophysiological conditions have not been elucidated. |
| 类目[WOS] | Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | RECEPTOR POTENTIAL CHANNELS ; OPERATED CA2+ ENTRY ; CATION CHANNEL ; ARRIVE GUIDELINES ; COUPLED RECEPTORS ; CONCISE GUIDE ; ION CHANNELS ; PHARMACOLOGY ; ACTIVATION ; NEURONS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356976300004 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/24937]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Texas Hlth Sci Ctr Houston, Dept Integrat Biol & Pharmacol, Houston, TX 77030 USA 2.Guangzhou Med Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China 3.Wuhan Univ, State Key Lab Virol, Key Lab Combinatorial Biosynth & Drug Discovery, Minist Educ,Sch Pharmaceut Sci, Wuhan 430072, Hubei, Peoples R China 4.Johns Hopkins Univ, Sch Med, Dept Neurosci, High Throughput Biol Ctr, Baltimore, MD 21205 USA 5.Johns Hopkins Univ, Johns Hopkins Ion Channel Ctr, Baltimore, MD USA 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Yingmin,Lu, Yungang,Qu, Chunrong,et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels[J]. BRITISH JOURNAL OF PHARMACOLOGY,2015,172(14):3495-3509. |
| APA | Zhu, Yingmin.,Lu, Yungang.,Qu, Chunrong.,Miller, Melissa.,Tian, Jinbin.,...&Luo, Huai-Rong.(2015).Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.BRITISH JOURNAL OF PHARMACOLOGY,172(14),3495-3509. |
| MLA | Zhu, Yingmin,et al."Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels".BRITISH JOURNAL OF PHARMACOLOGY 172.14(2015):3495-3509. |
入库方式： OAI收割
来源：昆明植物研究所
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