Hyperascyrones A-H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn.
文献类型：期刊论文
| 作者 | Zhu, Hucheng; Chen, Chunmei; Liu, Junjun; Sun, Bin; Wei, Guangzheng; Li, Yan ; Zhang, Jinwen; Yao, Guangmin; Luo, Zengwei; Xue, Yongbo
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| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2015-07-01 |
| 卷号 | 115页码:222-230 |
| 关键词 | Hypericum ascyron Linn. Hypericaceae Polycyclic polyprenylated acylphloroglucinols Polyprenylated spirocyclic acylphloroglucinol derivatives Cytotoxic activities Anti-HIV-1 activities |
| 英文摘要 | Eight polyprenylated spirocyclic acylphloroglucinol derivatives (PSAPs), hyperascyrones A-H, were isolated from the aerial parts of Hypericum ascyron Linn., together with six known analogs. Their structures were established by spectroscopic analyses including HRESIMS, 1D and 2D NMR, and their absolute configurations were determined by electronic circular dichroism calculations (ECD, Gaussian 09). Structures of previously reported tomoeones C, D, G, and H were revised. Hyperascyrones A-H were evaluated for their cytotoxic and anti-HIV-1 activities, with hyperascyrones C and G exhibiting significant cytotoxicities against HL-60 cell lines with IC50 values of 4.22 and 8.36 mu M, respectively. In addition, the chemotaxonomic significance of these compounds was also discussed. (C) 2015 Elsevier Ltd. All rights reserved. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | PHLOROGLUCINOL DERIVATIVES ; XANTHONES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000357237900022 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/24973]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhu, Hucheng,Chen, Chunmei,Liu, Junjun,et al. Hyperascyrones A-H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn.[J]. PHYTOCHEMISTRY,2015,115:222-230. |
| APA | Zhu, Hucheng.,Chen, Chunmei.,Liu, Junjun.,Sun, Bin.,Wei, Guangzheng.,...&Zhang, Yonghui.(2015).Hyperascyrones A-H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn..PHYTOCHEMISTRY,115,222-230. |
| MLA | Zhu, Hucheng,et al."Hyperascyrones A-H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn.".PHYTOCHEMISTRY 115(2015):222-230. |
入库方式： OAI收割
来源：昆明植物研究所
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