Cytotoxic prenylated flavonoids from Macaranga indica
文献类型：期刊论文
| 作者 | Yang, Da-Song; Peng, Wei-Bing; Yang, Yong-Ping ; Liu, Ke-Chun; Li, Xiao-Li; Xiao, Wei-Lie
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2015-06-01 |
| 卷号 | 103页码:187-191 |
| 关键词 | Macaranga indica Euphorbiaceae Prenylated flavonoids Ellagic acid Cytotoxicity |
| 英文摘要 | Three new prenylated flavonoids, macarindicins A-C (1-3), as well as seven known compounds (4-10) were isolated from the twigs of Macaranga indica. Their structures were elucidated on the basis of extensive spectroscopic interpretation. Compounds 2 and 3 enriched the diversity of prenyl moiety in genus Macaranga especially in the aspect of various lengths of prenyl chain. All the known compounds were isolated from M. indica for the first time and this plant was found to contain large number of ellagic acid. Compounds 1-10 were tested for their cytotoxicity against four cancer cell lines (MCF-7, Hep G2, Hela and P388) and showed IC50 values in the range of 2.61-20.35 mu g/mL. (C) 2015 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | PHENOLIC CONSTITUENTS ; AERIAL PARTS ; DENTICULATA ; LEAVES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356738800022 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/24940]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 推荐引用方式 GB/T 7714 | Yang, Da-Song,Peng, Wei-Bing,Yang, Yong-Ping,et al. Cytotoxic prenylated flavonoids from Macaranga indica[J]. FITOTERAPIA,2015,103:187-191. |
| APA | Yang, Da-Song,Peng, Wei-Bing,Yang, Yong-Ping,Liu, Ke-Chun,Li, Xiao-Li,&Xiao, Wei-Lie.(2015).Cytotoxic prenylated flavonoids from Macaranga indica.FITOTERAPIA,103,187-191. |
| MLA | Yang, Da-Song,et al."Cytotoxic prenylated flavonoids from Macaranga indica".FITOTERAPIA 103(2015):187-191. |
入库方式： OAI收割
来源：昆明植物研究所
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