Retinoblastoma-binding Protein 1 Has an Interdigitated Double Tudor Domain with DNA Binding Activity*
文献类型:期刊论文
作者 | Gong, Weibin1; Wang, Jinfeng1; Perrett, Sarah1; Feng, Yingang2 |
刊名 | JOURNAL OF BIOLOGICAL CHEMISTRY
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出版日期 | 2014-02-21 |
卷号 | 289期号:8页码:4882-4895 |
关键词 | DNA-binding Protein Epigenetics Nuclear Magnetic Resonance Protein Structure Tumor Suppressor Gene |
英文摘要 | Background: Retinoblastoma-binding protein 1 (RBBP1), a tumor suppressor, has a Tudor domain with unknown function. Results: The Tudor domain adopts an interdigitated double Tudor structure with DNA binding activity. Conclusion: The Tudor domain of the RBBP1 family is a DNA binding module. Significance: Our research provides further structural insights into RBBP1 function and the diversity of Tudor domains. |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
类目[WOS] | Biochemistry & Molecular Biology |
研究领域[WOS] | Biochemistry & Molecular Biology |
关键词[WOS] | FAMILY PROTEINS ; MACROMOLECULAR STRUCTURE ; DEACETYLASE COMPLEX ; STRUCTURAL BASIS ; NOE ASSIGNMENT ; BREAST-CANCER ; GROWTH ARREST ; NMR ; RBP1 ; IDENTIFICATION |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000331607900035 |
公开日期 | 2015-12-24 |
源URL | [http://ir.qibebt.ac.cn/handle/337004/6142] ![]() |
专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
作者单位 | 1.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Peoples R China |
推荐引用方式 GB/T 7714 | Gong, Weibin,Wang, Jinfeng,Perrett, Sarah,et al. Retinoblastoma-binding Protein 1 Has an Interdigitated Double Tudor Domain with DNA Binding Activity*[J]. JOURNAL OF BIOLOGICAL CHEMISTRY,2014,289(8):4882-4895. |
APA | Gong, Weibin,Wang, Jinfeng,Perrett, Sarah,&Feng, Yingang.(2014).Retinoblastoma-binding Protein 1 Has an Interdigitated Double Tudor Domain with DNA Binding Activity*.JOURNAL OF BIOLOGICAL CHEMISTRY,289(8),4882-4895. |
MLA | Gong, Weibin,et al."Retinoblastoma-binding Protein 1 Has an Interdigitated Double Tudor Domain with DNA Binding Activity*".JOURNAL OF BIOLOGICAL CHEMISTRY 289.8(2014):4882-4895. |
入库方式: OAI收割
来源:青岛生物能源与过程研究所
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