Resonance assignments of the periplasmic domain of a cellulose-sensing trans-membrane anti-sigma factor from Clostridium thermocellum
文献类型：期刊论文
| 作者 | Ding, Xiaoke1,2; Chen, Chao2,3 ; Cui, Qiu2,3,4; Li, Wenli1; Feng, Yingang2,3
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| 刊名 | BIOMOLECULAR NMR ASSIGNMENTS
 |
| 出版日期 | 2015-10-01 |
| 卷号 | 9期号:2页码:321-324 |
| 关键词 | Anti-sigma factor Clostridium thermocellum NMR Chemical shift assignment Periplasmic domain |
| 英文摘要 | The cellulosome of Clostridium thermocellum is an elegant and efficient multi-enzyme complex for degrading lignocellulose. The cellulosome contains several dozens of carbohydrate hydrolysis enzymes, which are regulated by the presence of environmental substrates through several pairs of sigma and anti-sigma factors. The anti-sigma factors sense the presence of substrates and transduce the signals into the cell. The sigma factors are then released from the corresponding anti-sigma factors, and they recruit RNA polymerase to transcribe specific cellulosomal genes. However, it is not clear how the extracellular signals are transduced into the cell by the anti-sigma factors. The anti-sigma factors of C. thermocellum contain an N-terminal intracellular domain, a trans-membrane helix, a periplasmic domain, a proline-rich region which is probably required for crossing the cell wall, and a C-terminal carbohydrate-binding domain or glycoside hydrolase domain. The periplasmic domain may play a key role in signal transduction; however, its three-dimensional structure is still unknown. Here we report the NMR resonance assignments of the periplasmic domain of anti-sigma factor RsgI2 from C. thermocellum as a basis for further structural determination and functional studies. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| 类目[WOS] | Biophysics ; Spectroscopy |
| 研究领域[WOS] | Biophysics ; Spectroscopy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361440100022 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/6600]  |
| 专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
| 作者单位 | 1.Ocean Univ China, Minist Educ, Sch Med & Pharm, Key Lab Marine Drugs, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Peoples R China 4.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Xiaoke,Chen, Chao,Cui, Qiu,et al. Resonance assignments of the periplasmic domain of a cellulose-sensing trans-membrane anti-sigma factor from Clostridium thermocellum[J]. BIOMOLECULAR NMR ASSIGNMENTS,2015,9(2):321-324. |
| APA | Ding, Xiaoke,Chen, Chao,Cui, Qiu,Li, Wenli,&Feng, Yingang.(2015).Resonance assignments of the periplasmic domain of a cellulose-sensing trans-membrane anti-sigma factor from Clostridium thermocellum.BIOMOLECULAR NMR ASSIGNMENTS,9(2),321-324. |
| MLA | Ding, Xiaoke,et al."Resonance assignments of the periplasmic domain of a cellulose-sensing trans-membrane anti-sigma factor from Clostridium thermocellum".BIOMOLECULAR NMR ASSIGNMENTS 9.2(2015):321-324. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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