Protein-protein complexation in bioluminescence
文献类型：期刊论文
| 作者 | Titushin, Maxim S.1; Feng, Yingang2 ; Lee, John3; Vysotski, Eugene S.4; Liu, Zhi-Jie1
|
| 刊名 | PROTEIN & CELL
 |
| 出版日期 | 2011-12-01 |
| 卷号 | 2期号:12页码:957-972 |
| 关键词 | green-fluorescent protein (GFP) photoprotein luciferase lumazine protein Forster resonance energy transfer (FRET) docking |
| 英文摘要 | In this review we summarize the progress made towards understanding the role of protein-protein interactions in the function of various bioluminescence systems of marine organisms, including bacteria, jellyfish and soft corals, with particular focus on methodology used to detect and characterize these interactions. In some bioluminescence systems, protein-protein interactions involve an "accessory protein" whereby a stored substrate is efficiently delivered to the bioluminescent enzyme luciferase. Other types of complexation mediate energy transfer to an "antenna protein" altering the color and quantum yield of a bioluminescence reaction. Spatial structures of the complexes reveal an important role of electrostatic forces in governing the corresponding weak interactions and define the nature of the interaction surfaces. The most reliable structural model is available for the protein-protein complex of the Ca2+-regulated photoprotein clytin and green-fluorescent protein (GFP) from the jellyfish Clytia gregaria, solved by means of X-ray crystallography, NMR mapping and molecular docking. This provides an example of the potential strategies in studying the transient complexes involved in bioluminescence. It is emphasized that structural studies such as these can provide valuable insight into the detailed mechanism of bioluminescence. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Cell Biology |
| 研究领域[WOS] | Cell Biology |
| 关键词[WOS] | GREEN-FLUORESCENT PROTEIN ; LUCIFERIN-BINDING-PROTEIN ; RENILLA-RENIFORMIS LUCIFERASE ; VIBRIO-FISCHERI Y1 ; JELLYFISH CLYTIA-GREGARIA ; ALPHA/BETA-HYDROLASE FOLD ; AMINO-ACID-SEQUENCE ; BACTERIAL LUCIFERASE ; ENERGY-TRANSFER ; CRYSTAL-STRUCTURE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310522900005 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/6641]  |
| 专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
| 作者单位 | 1.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 3.Univ Georgia, Dept Biochem & Mol Biol, Athens, GA 30602 USA 4.Russian Acad Sci, Siberian Branch, Inst Biophys, Lab Photobiol, Krasnoyarsk 660036, Russia |
| 推荐引用方式 GB/T 7714 | Titushin, Maxim S.,Feng, Yingang,Lee, John,et al. Protein-protein complexation in bioluminescence[J]. PROTEIN & CELL,2011,2(12):957-972. |
| APA | Titushin, Maxim S.,Feng, Yingang,Lee, John,Vysotski, Eugene S.,&Liu, Zhi-Jie.(2011).Protein-protein complexation in bioluminescence.PROTEIN & CELL,2(12),957-972. |
| MLA | Titushin, Maxim S.,et al."Protein-protein complexation in bioluminescence".PROTEIN & CELL 2.12(2011):957-972. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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