High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp SD301
文献类型：期刊论文
| 作者 | Song, Xiaojin1,2 ; Wang, Xiaolong4; Tan, Yanzhen1,2; Feng, Yingang1,2; Li, Wenli4; Cui, Qiu1,2,3
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| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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| 出版日期 | 2015-09-30 |
| 卷号 | 63期号:38页码:8445-8451 |
| 关键词 | marine fungi optimization Pseudozyma squalene |
| 英文摘要 | A yeast-like fungus, termed strain SD301, with the ability to produce a high concentration of squalene, was isolated from Shuidong Bay, China. The nucleotide sequence analysis of the internal transcribed spacer (ITS) region of SD301 indicated the strain belonged to Pseudozyma species. The highest biomass and squalene production of SD301 were obtained when glucose and yeast extracts were used as the carbon and nitrogen sources, respectively, with a C/N ratio of 3. The optimal pH and temperature were 6 and 25 degrees C, with 15 g L-1 of supplemented sea salt. The maximum squalene productivity reached 0.039 g L(-1)h(-1) in batch fermentation, while the maximum squalene yield of 2.445 g L-1 was obtained in fed-batch fermentation. According to our knowledge, this is the highest squalene yield produced thus far using fermentation technology, and the newly isolated strain Pseudozyma sp. SD301 is a promising candidate for commercial squalene production. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 类目[WOS] | Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology |
| 研究领域[WOS] | Agriculture ; Chemistry ; Food Science & Technology |
| 关键词[WOS] | THRAUSTOCHYTRID AURANTIOCHYTRIUM SP ; OLIVE OIL ; SACCHAROMYCES-CEREVISIAE ; ENHANCED PRODUCTION ; OPTIMIZATION ; EXTRACTION ; MANGROVEI ; 18W-13A ; CANCER ; METAL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000362243100011 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/6686]  |
| 专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Shandong, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Shandong, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Shandong, Peoples R China 4.Ocean Univ China, Sch Med & Pharm, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Xiaojin,Wang, Xiaolong,Tan, Yanzhen,et al. High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp SD301[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2015,63(38):8445-8451. |
| APA | Song, Xiaojin,Wang, Xiaolong,Tan, Yanzhen,Feng, Yingang,Li, Wenli,&Cui, Qiu.(2015).High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp SD301.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,63(38),8445-8451. |
| MLA | Song, Xiaojin,et al."High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp SD301".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63.38(2015):8445-8451. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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