AhR-active compounds in sediments of the Haihe and Dagu Rivers, China
文献类型：期刊论文
| 作者 | Song, Maoyong; Jiang, Qinting; Xu, Yan; Liu, Hanxia; Lam, Paul K. S.; O'Toole, Desmond K.; Zhang, Qinghua; Giesy, John P.; Jiang, Guibin |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2006 |
| 卷号 | 63期号:7页码:1222-1230 |
| 关键词 | H4IIE-luc dioxin PCBs |
| 英文摘要 | Total concentrations of compounds that can cause activation of the aryl hydrocarbon receptor (AhR) in extracts of river sediments from various locations in the Haihe and Dagu Rivers, Tianjin, China were determined by use of the in vitro H4IIE-luc cell line. AhR-active compounds were isolated from sediments by Soxhlet extraction, and the crude extracts were fractionated using a Florisil column into three Fractions. The response of samples was compared to the TCDD standard and expressed as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalents (TCDD-EQs). Significant dioxin-like activity was observed in each sample. The TCDD-EQs in crude extracts of sediments (SCEs), as determined with the bioassay were 2-4 times greater than the sum of the TCDD-EQs of the eluent from fractions separated with a Florisil column. The results also showed that Fractions 2 and 3 contained most of the AhR-mediated activity. The results obtained by using the bioassay were compared with those of previous measurements of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) and the structurally-similar AhR-active polychlorinated biphenyls (PCBs). It was determined that sediments from the Dagu River contained greater concentrations of TCDD-EQ than did sediments from the Haihe River except at Jingangqiao (location R3), which is associated with industrial activities in the adjacent densely populated area. The concentrations of TCDD-EQs, based on the EC20 and the relative potency ranges, of SCEs ranged from 330 to 930 and 1200 to 13 900 pg TCDD-EQ g(-1) dry wt in Haihe and Dagu Rivers, respectively. (c) 2005 Elsevier Ltd. All rights reserved. |
| WOS记录号 | WOS:000237838900020 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/22826]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Song, Maoyong,Jiang, Qinting,Xu, Yan,et al. AhR-active compounds in sediments of the Haihe and Dagu Rivers, China[J]. CHEMOSPHERE,2006,63(7):1222-1230. |
| APA | Song, Maoyong.,Jiang, Qinting.,Xu, Yan.,Liu, Hanxia.,Lam, Paul K. S..,...&Jiang, Guibin.(2006).AhR-active compounds in sediments of the Haihe and Dagu Rivers, China.CHEMOSPHERE,63(7),1222-1230. |
| MLA | Song, Maoyong,et al."AhR-active compounds in sediments of the Haihe and Dagu Rivers, China".CHEMOSPHERE 63.7(2006):1222-1230. |
入库方式： OAI收割
来源：生态环境研究中心
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