Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride
文献类型：期刊论文
| 作者 | Liao, Chun-Yang; Fu, Jian-Jie; Shi, Jian-Bo; Zhou, Qun-Fang; Yuan, Chun-Gang; Jiang, Gui-Bin |
| 刊名 | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
 |
| 出版日期 | 2006 |
| 卷号 | 22期号:2页码:225-233 |
| 关键词 | methylmercury medaka histopathological change cholinesterase activity |
| 英文摘要 | A series of specific toxicological effects including bioaccumulation of the pollutant, histological changes and influences on cholinesterase (ChE) activities were examined in the adult Japanese medaka after the exposure to graded sublethal concentrations (40, 20, 10, 5, 2.5 ng Hg/mL) of methylmercury chloride (MMC). Methylmercury (MeHg) contents in the exposed medaka tissues ranged from 0.03 to 64.4 mu g Hg/g (wet weight, w.w.). High concentrations of MeHg were accumulated in the liver and brain, while the concentrations in muscle and fat were relatively low. A dose-dependent and exposure time-dependent increase of MeHg contents in tissues was observed. Histopathological changes, such as oedema, vacuolization, pyknotic nucleus, telangiectasis, and degenerative sperm, can clearly be observed in the slices from the liver, gill, and male gonad of the exposed medaka. Inhibition of ChE activity was common in the exposed fish's brain, liver, gill, and muscle. The serious intoxication of MMC to medaka was definitely demonstrated herein. (c) 2006 Published by Elsevier B.V. |
| WOS记录号 | WOS:000239683900018 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/22896]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liao, Chun-Yang,Fu, Jian-Jie,Shi, Jian-Bo,et al. Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2006,22(2):225-233. |
| APA | Liao, Chun-Yang,Fu, Jian-Jie,Shi, Jian-Bo,Zhou, Qun-Fang,Yuan, Chun-Gang,&Jiang, Gui-Bin.(2006).Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,22(2),225-233. |
| MLA | Liao, Chun-Yang,et al."Methylmercury accumulation, histopathology effects, and cholinesterase activity alterations in medaka (Oryzias latipes) following sublethal exposure to methylmercury chloride".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 22.2(2006):225-233. |
入库方式： OAI收割
来源：生态环境研究中心
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