Stereoselective synthesis of jaspine B from D-xylose
文献类型：期刊论文
| 作者 | Liu, Jun; Du, Yuguo; Dong, Xiaomin; Meng, Shucong; Xiao, Junjun; Cheng, Lijian |
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 2006 |
| 卷号 | 341期号:16页码:2653-2657 |
| 关键词 | natural products jaspine B antitumor activity carbohydrates total synthesis |
| 英文摘要 | The natural cytotoxic marine compound, jaspine B, is stereo selectively synthesized from D-Xylose in 11 linear steps with a 23.9% overall yield. The key step in the synthesis involves an iodine-induced debenzylation of a primary alcohol and the subsequent 2,5-cyclization to fit the required configuration of jaspine B. A preliminary bioassay shows strong inhibition activities against human MDA231, Hela, and CNE cell lines, indicating potential usage in various cancer treatments. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS记录号 | WOS:000242007800003 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/22930]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Jun,Du, Yuguo,Dong, Xiaomin,et al. Stereoselective synthesis of jaspine B from D-xylose[J]. CARBOHYDRATE RESEARCH,2006,341(16):2653-2657. |
| APA | Liu, Jun,Du, Yuguo,Dong, Xiaomin,Meng, Shucong,Xiao, Junjun,&Cheng, Lijian.(2006).Stereoselective synthesis of jaspine B from D-xylose.CARBOHYDRATE RESEARCH,341(16),2653-2657. |
| MLA | Liu, Jun,et al."Stereoselective synthesis of jaspine B from D-xylose".CARBOHYDRATE RESEARCH 341.16(2006):2653-2657. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。