The first total synthesis of sporiolide A
文献类型：期刊论文
| 作者 | Du, Yuguo; Chen, Qi; Linhardt, Robert J. |
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2006 |
| 卷号 | 71期号:22页码:8446-8451 |
| 英文摘要 | The first total synthesis of the natural cytotoxic agent sporiolide A has been accomplished from D-glucal in 16 steps with 6.1% overall yield. Carbohydrates were applied as the chiral templates to manipulate the absolute configuration during the synthesis. Pyridinium chlorochromate (PCC)-promoted transformation of the cyclic enol-ether to lactone, followed by Yamaguchi esterification and intramolecular ring closure metathesis, greatly facilitates synthesis of the target compound. |
| WOS记录号 | WOS:000241435600016 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/22934]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Du, Yuguo,Chen, Qi,Linhardt, Robert J.. The first total synthesis of sporiolide A[J]. JOURNAL OF ORGANIC CHEMISTRY,2006,71(22):8446-8451. |
| APA | Du, Yuguo,Chen, Qi,&Linhardt, Robert J..(2006).The first total synthesis of sporiolide A.JOURNAL OF ORGANIC CHEMISTRY,71(22),8446-8451. |
| MLA | Du, Yuguo,et al."The first total synthesis of sporiolide A".JOURNAL OF ORGANIC CHEMISTRY 71.22(2006):8446-8451. |
入库方式： OAI收割
来源：生态环境研究中心
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