中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector

文献类型:期刊论文

作者Zheng, ZX; Wei, YL; Lin, JM
刊名ELECTROPHORESIS
出版日期2005
卷号26期号:2015-04-05页码:1007-1012
关键词chiral separation ligand-exchange capillary electrophoresis ornithine
英文摘要A ligand-exchange capillary electrophoresis was explored, with L-ornithine as the ligand and copper(II) as the central ion. Its applicability was demonstrated with unde rivatized and dansyl amino acids, a dipepticle, and drugs with amino alcohol structure. The enantioselectivity was found to be strongly dependent on pH and copper(II)-L-Orn complex concentration. Due to the adsorption of the positively charged species onto the capillary inner walls, the chiral separation selectivity is very high while the efficiency is relatively low. Permanent 1,3-propanediamine-coated capillaries show an improved separation efficiency and theoret cal plate numbers increasing from 10(4) to 10(5). Similar phenomena were observed when sodium dodecyl sulfate (SDS) micelles were added to the copper(II) complex solution. The poor separation efficiency of chiral compounds in uncoated capillaries may result from the low rate of the ligand-exchange reactions, and the high enantioselectivity may derive from the complexing process in the adsorbed phase.
学科主题Biochemistry & Molecular Biology; Chemistry
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
WOS记录号WOS:000227425400033
源URL[http://ir.rcees.ac.cn/handle/311016/23150]  
专题生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式
GB/T 7714
Zheng, ZX,Wei, YL,Lin, JM. Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector[J]. ELECTROPHORESIS,2005,26(2015-04-05):1007-1012.
APA Zheng, ZX,Wei, YL,&Lin, JM.(2005).Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector.ELECTROPHORESIS,26(2015-04-05),1007-1012.
MLA Zheng, ZX,et al."Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector".ELECTROPHORESIS 26.2015-04-05(2005):1007-1012.

入库方式: OAI收割

来源:生态环境研究中心

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。