Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector
文献类型：期刊论文
| 作者 | Zheng, ZX; Wei, YL; Lin, JM |
| 刊名 | ELECTROPHORESIS
 |
| 出版日期 | 2005 |
| 卷号 | 26期号:2015-04-05页码:1007-1012 |
| 关键词 | chiral separation ligand-exchange capillary electrophoresis ornithine |
| 英文摘要 | A ligand-exchange capillary electrophoresis was explored, with L-ornithine as the ligand and copper(II) as the central ion. Its applicability was demonstrated with unde rivatized and dansyl amino acids, a dipepticle, and drugs with amino alcohol structure. The enantioselectivity was found to be strongly dependent on pH and copper(II)-L-Orn complex concentration. Due to the adsorption of the positively charged species onto the capillary inner walls, the chiral separation selectivity is very high while the efficiency is relatively low. Permanent 1,3-propanediamine-coated capillaries show an improved separation efficiency and theoret cal plate numbers increasing from 10(4) to 10(5). Similar phenomena were observed when sodium dodecyl sulfate (SDS) micelles were added to the copper(II) complex solution. The poor separation efficiency of chiral compounds in uncoated capillaries may result from the low rate of the ligand-exchange reactions, and the high enantioselectivity may derive from the complexing process in the adsorbed phase. |
| 学科主题 | Biochemistry & Molecular Biology; Chemistry |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry |
| WOS记录号 | WOS:000227425400033 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23150]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zheng, ZX,Wei, YL,Lin, JM. Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector[J]. ELECTROPHORESIS,2005,26(2015-04-05):1007-1012. |
| APA | Zheng, ZX,Wei, YL,&Lin, JM.(2005).Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector.ELECTROPHORESIS,26(2015-04-05),1007-1012. |
| MLA | Zheng, ZX,et al."Chiral separation based on ligand-exchange capillary electrophoresis using a copper(II)-L-ornithine ternary complex as selector".ELECTROPHORESIS 26.2015-04-05(2005):1007-1012. |
入库方式： OAI收割
来源：生态环境研究中心
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