Hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres containing L-proline for chiral separation of amino acids
文献类型：期刊论文
| 作者 | Chai, ZK; Xu, SG; Hou, XP |
| 刊名 | CHROMATOGRAPHIA
 |
| 出版日期 | 2004 |
| 卷号 | 60期号:1页码:25-31 |
| 关键词 | column liquid chromatography chiral separations hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres amino acids |
| 英文摘要 | A new packing material for ligand-exchange chromatography, L-proline-modified hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres, has been prepared and evaluated. The microspheres, prepared by a one-step swelling and polymerization method, have a narrow bead size (as determined by scanning electron microscopy, SEM), a broad pore-size distribution (by nitrogen adsorption) and, especially, inhomogeneous structural composition (by differential scanning calorimetry). The support, which has an L-proline content of 0.35 mmol g(-1) (nitrogen analysis), provides good enantioselectivity and column efficiency. Twenty-three of the twenty-four common D,L-amino acids tested were resolved on a 250 mm x 4.6 mm i.d. column and mixtures of up to seven racemic amino acids were easily separated into their enantiomers. Two average pore diameters, volume-average (00 and surface-average (d(s)) pore diameters, are defined. The ratio d(v)/d(s) is used to characterize the broadness of the pore-size distribution. It is shown that the widely used formula d = 4V(p)/S for cylindrical pores, where V-p is pore volume and S the specific surface area, gives the surface-average pore diameter. |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry |
| WOS记录号 | WOS:000224100500005 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23452]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Chai, ZK,Xu, SG,Hou, XP. Hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres containing L-proline for chiral separation of amino acids[J]. CHROMATOGRAPHIA,2004,60(1):25-31. |
| APA | Chai, ZK,Xu, SG,&Hou, XP.(2004).Hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres containing L-proline for chiral separation of amino acids.CHROMATOGRAPHIA,60(1),25-31. |
| MLA | Chai, ZK,et al."Hydrolyzed vinyl acetate-divinylbenzene copolymer microspheres containing L-proline for chiral separation of amino acids".CHROMATOGRAPHIA 60.1(2004):25-31. |
入库方式： OAI收割
来源：生态环境研究中心
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