Chiral separation of underivatized and dansyl amino acids by ligand-exchange micellar electrokinetic capillary chromatography using a copper(II)-L-valine complex as selector
文献类型：期刊论文
| 作者 | Zheng, ZX; Lin, JM; Qu, F |
| 刊名 | JOURNAL OF CHROMATOGRAPHY A
 |
| 出版日期 | 2003 |
| 卷号 | 1007期号:1页码:189-196 |
| 关键词 | ligand-exchange micellar electrokinetic capillary chromatography enantiomer separation amino acids amino acids Dns derivatives valine |
| 英文摘要 | Ligand-exchange micellar electrokinetic capillary chromatography was used for the chiral resolution of underivatized and dansyl amino acid enantiomers simultaneously. The separation was achieved by chiral copper(II)-L-valine complexes incorporated in micelles of sodium dodecyl sulfate (SIDS). The enantioresolution was strongly affected by SDS and a concentration of 20 mM SDS was shown to be necessary for the separation. Other impacting factors were investigated including pH. the molar ratio of copper(II) to L-valine and the total concentration of complex. Using the proposed method, I I different dansyl amino acids and two underivatized amino acids were separated successfully with a running electrolyte of 20 mM NH4OAc. 4 mM CuSO4, 8 MM L-valine and 20 mM SDS at pH 9.0 in less than 25 min. Experiments were also performed with other amino acid ligands in order to vary the stability and the sterical arrangement of the copper(II) complexes and the possible chiral recognition mechanism was also discussed briefly. (C) 2003 Elsevier B.V. All rights reserved. |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry |
| WOS记录号 | WOS:000184395900020 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23669]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zheng, ZX,Lin, JM,Qu, F. Chiral separation of underivatized and dansyl amino acids by ligand-exchange micellar electrokinetic capillary chromatography using a copper(II)-L-valine complex as selector[J]. JOURNAL OF CHROMATOGRAPHY A,2003,1007(1):189-196. |
| APA | Zheng, ZX,Lin, JM,&Qu, F.(2003).Chiral separation of underivatized and dansyl amino acids by ligand-exchange micellar electrokinetic capillary chromatography using a copper(II)-L-valine complex as selector.JOURNAL OF CHROMATOGRAPHY A,1007(1),189-196. |
| MLA | Zheng, ZX,et al."Chiral separation of underivatized and dansyl amino acids by ligand-exchange micellar electrokinetic capillary chromatography using a copper(II)-L-valine complex as selector".JOURNAL OF CHROMATOGRAPHY A 1007.1(2003):189-196. |
入库方式： OAI收割
来源：生态环境研究中心
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