Investigation of protein-styrene oxide adducts as a molecular biomarker of human exposed to styrene
文献类型：期刊论文
| 作者 | Liu, SF; Fang, QM; Jin, ZL; Rappaport, MS |
| 刊名 | JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA
 |
| 出版日期 | 2001 |
| 卷号 | 13期号:4页码:391-397 |
| 关键词 | protein adduct styrene oxide molecular biomarker |
| 英文摘要 | Hemoglobin-styrene oxide adducts in blood have been studied as a molecular biomarker of worker exposed to styrene. Determination of protein-styrene oxide adducts in different biological samples with modified Raney-Ni procedure is described in this paper. The following biological samples have been investigated: fresh rat blood reacted with styrene oxide in vitro; rat blood reacted with styrene or styrene oxide in vivo; vein blood from workers exposed to styrene in two factories. The data showed that there was a good linear dose-response relationship between reacting dose of styrene oxide or styrene and amount of protein-styrene oxide adducts in both in vitro and in vivo experiments. For human samples, a dose-response relationship between protein adducts and styrene exposure can be found in glass fiber factory, but not in piano manufacture plant. |
| WOS记录号 | WOS:000174780600002 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/24019]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, SF,Fang, QM,Jin, ZL,et al. Investigation of protein-styrene oxide adducts as a molecular biomarker of human exposed to styrene[J]. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,2001,13(4):391-397. |
| APA | Liu, SF,Fang, QM,Jin, ZL,&Rappaport, MS.(2001).Investigation of protein-styrene oxide adducts as a molecular biomarker of human exposed to styrene.JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,13(4),391-397. |
| MLA | Liu, SF,et al."Investigation of protein-styrene oxide adducts as a molecular biomarker of human exposed to styrene".JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA 13.4(2001):391-397. |
入库方式： OAI收割
来源：生态环境研究中心
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