Bioconcentration, elimination and metabolism of 2,4-dinitrotoluene in carps (Cyprinus carpio L.)
文献类型：期刊论文
| 作者 | Lang, PZ; Chen, DB; Wang, N; Wang, Y; Ding, YZ |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 1997 |
| 卷号 | 18期号:10页码:1607-1610 |
| 关键词 | 2 carps peaky bioconcentration curve 4-dinitrotoluene (2 4-DNT) |
| 英文摘要 | Bioconcentration curves of 2,4-DNT in carps(whole fish, liver, intestine) were investigated using semistatic systems. For whole fish, its curve could be described as a gentle peak which began with a rise in concentration to steady state, then declined and reached lower level followed by another steady state. For liver and intestine, their curves both contained two successive peaks. Bioconcentration factors(BCFs) of 2,4-DNT in whole fish at the first and second steady state were 9.15 and 4.15 respectively. By logarithmic plotting, two straight lines with different slopes 3.6 and 0.1 d(-1) were measured for elimination. Two metabolites were isolated by HPLC as 4-amino-2-nitrotoluene and 2,4-diaminotoluene, their retention times were 23.1 and 8.8 min respectively. A one-compartment model was set up to simulate the uptake, in which biotransformation adhered to delayed enzyme-catalytic logarithmic kinetics. Modelling curve was in accord with measured values. |
| WOS记录号 | WOS:A1997YC46500009 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/24341]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Lang, PZ,Chen, DB,Wang, N,et al. Bioconcentration, elimination and metabolism of 2,4-dinitrotoluene in carps (Cyprinus carpio L.)[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,1997,18(10):1607-1610. |
| APA | Lang, PZ,Chen, DB,Wang, N,Wang, Y,&Ding, YZ.(1997).Bioconcentration, elimination and metabolism of 2,4-dinitrotoluene in carps (Cyprinus carpio L.).CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,18(10),1607-1610. |
| MLA | Lang, PZ,et al."Bioconcentration, elimination and metabolism of 2,4-dinitrotoluene in carps (Cyprinus carpio L.)".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 18.10(1997):1607-1610. |
入库方式： OAI收割
来源：生态环境研究中心
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