Biomarker responses and reproductive toxicity of the effluent from a Chinese large sewage treatment plant in Japanese medaka (Oryzias latipes)
文献类型：期刊论文
| 作者 | Ma, TW; Wan, XQ; Huang, QH; Wang, ZJ; Liu, JK |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2005 |
| 卷号 | 59期号:2页码:281-288 |
| 关键词 | biomarker reproductive toxicity vitellogenin CYP1A sewage effluent Japanese medaka |
| 英文摘要 | The present study was conducted to assess the potential toxicity of the effluent from a large sewage treatment plant (GBD-STP) in Beijing. Japanese medakas (Oryzias latipes) at reproduction active period were exposed to a serial of graded concentrations of the effluent or 100 ng l(-1) of 17-alpha-ethinylestradiol (EE2, positive control). Growth, gonadosomatic index (GSI), hepatosomatic index (HSI), reproductive success, induction potency of vitellogenin (VTG) in male fish and that of 7-ethoxyresorufin-o-deethylase activity (EROD) in male fish liver were used as test endpoints. The growth suppression of fish was observed in a dose-dependent manner, resulting in significant differences in both body length and body weight of medaka above 5% effluent. This effluent can inhibit the growth of gonad of medakas and are more sensitive to male than to female. At exposure concentration of 40% and higher, there was an unexpected decrease of HSI values, which may be resulted from sub-lethal toxicity of effluent to fish liver. VTG of plasma in males were induced in all exposure concentration levels, but not in a dose-dependent manner. The concentration of 5% effluent would be the lowest observed adverse effect level (LOAEL) affecting reproductive success when examining fertile individuals, fecundity and fertilization rate. The overt CYP1A response and higher reproductive toxicity may be indicative of low process efficiency of this STP. (c) 2004 Elsevier Ltd. All rights reserved. |
| 学科主题 | Environmental Sciences & Ecology |
| 研究领域[WOS] | Environmental Sciences & Ecology |
| WOS记录号 | WOS:000227822200015 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23271]  |
| 专题 | 生态环境研究中心_环境水质学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ma, TW,Wan, XQ,Huang, QH,et al. Biomarker responses and reproductive toxicity of the effluent from a Chinese large sewage treatment plant in Japanese medaka (Oryzias latipes)[J]. CHEMOSPHERE,2005,59(2):281-288. |
| APA | Ma, TW,Wan, XQ,Huang, QH,Wang, ZJ,&Liu, JK.(2005).Biomarker responses and reproductive toxicity of the effluent from a Chinese large sewage treatment plant in Japanese medaka (Oryzias latipes).CHEMOSPHERE,59(2),281-288. |
| MLA | Ma, TW,et al."Biomarker responses and reproductive toxicity of the effluent from a Chinese large sewage treatment plant in Japanese medaka (Oryzias latipes)".CHEMOSPHERE 59.2(2005):281-288. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。