One-pot three-component reactions of methyl ketones, phenols and a nucleophile: an expedient way to synthesize densely substituted benzofurans
文献类型:期刊论文
作者 | Cheng, Cheng1; Liu, Changhui1; Gu YL(顾彦龙)1,2 |
刊名 | Tetrahedron
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出版日期 | 2015 |
卷号 | 71期号:42页码:8009-8017 |
关键词 | Multi-component reactions Benzofurans Methyl ketone Phenylglyoxal |
ISSN号 | 0040-4020 |
通讯作者 | 顾彦龙 |
英文摘要 | Three-component reactions of phenylglyoxal monohydrate, phenols, and indoles were developed with the aid of acid-catalyst, which produced various densely substituted benzofurans with good to excellent yields. On the basis of this observation, a one-pot, step-wise reaction was developed by using methyl ketones instead of using phenylglyoxal component in I2/DMSO system. At last, three-component reaction offered a useful way to synthesize densely substituted benzofurans starting from simple and easily available substrates. The indole component can be replaced by some other nucleophiles, such as 1,2,4-trimethoxybenzene and thiophenol. |
学科主题 | 物理化学与绿色催化 |
收录类别 | SCI |
资助信息 | National Natural Science Foundation of China (21173089;21373093);Chutian Scholar Program of the Hubei Provincial Government and the Cooperative Innovation Center of Hubei Province; the Fundamental Research Funds for the Central Universities of China (2014ZZGH019) |
语种 | 英语 |
WOS记录号 | WOS:000361865100007 |
源URL | [http://210.77.64.217/handle/362003/18677] ![]() |
专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
作者单位 | 1.Huazhong Univ Sci & Technol, Key Lab Large Format Battery Mat & Syst, Minist Educ, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China 2.Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Cheng, Cheng,Liu, Changhui,Gu YL. One-pot three-component reactions of methyl ketones, phenols and a nucleophile: an expedient way to synthesize densely substituted benzofurans[J]. Tetrahedron,2015,71(42):8009-8017. |
APA | Cheng, Cheng,Liu, Changhui,&Gu YL.(2015).One-pot three-component reactions of methyl ketones, phenols and a nucleophile: an expedient way to synthesize densely substituted benzofurans.Tetrahedron,71(42),8009-8017. |
MLA | Cheng, Cheng,et al."One-pot three-component reactions of methyl ketones, phenols and a nucleophile: an expedient way to synthesize densely substituted benzofurans".Tetrahedron 71.42(2015):8009-8017. |
入库方式: OAI收割
来源:兰州化学物理研究所
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