Preparation and application of a novel mixed-mode monolith for reversed-phase and per aqueous capillary electrochromatography
文献类型：期刊论文
| 作者 | Tang S(汤胜)1,2 ; Guo Y(郭勇)1; Liang XJ(梁晓静)1; Wei, Falin3; Yang, Limin3; Liu SJ(刘淑娟)1; Liu X(刘霞)1; Jiang SX(蒋生祥)1; Liu SJ(刘淑娟); Liu X(刘霞)
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| 刊名 | Analytical Methods
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| 出版日期 | 2015 |
| 卷号 | 7期号:11页码:4750-4756 |
| ISSN号 | 1759-9660 |
| 通讯作者 | 刘淑娟 ; 刘霞 |
| 英文摘要 | A novel mixed-mode monolithic stationary phase based on bonding of 4,5-imidazoledicarboxy acid to the surface of an organic-silica hybrid monolith was prepared and characterized. Satisfactory characteristics in terms of mechanical stability, permeability and reproducibility of the resultant monolithic column were achieved. A typical per aqueous chromatographic behavior was observed in water-rich mobile phases. The resultant monolithic column was applied for the efficient resolution of various polar and hydrophilic compounds under per aqueous or reversed-phase chromatographic conditions, which successfully demonstrated its suitability for the analysis of these polar compounds in highly aqueous mobile phases. The highest column efficiency obtained for the amines was 149 000 N m−1. The experimental results showed that the mixed-mode mechanism of hydrophobic and ion-exchange interactions was involved in the separation under the given conditions. The successful applications suggested that the mixed-mode organic-silica hybrid monolithic column could offer a wide range of retention behaviors and flexible selectivities toward polar compounds, achieving various target separations. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (nos. 21475143;21175143;20905072);the National Science & Technology Major Project of China (nos. 2011ZX05010-003;2011ZX05011) |
| 语种 | 英语 |
| WOS记录号 | WOS:000355557500043 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://210.77.64.217/handle/362003/18468]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Liu SJ(刘淑娟); Liu X(刘霞) |
| 作者单位 | 1.Key Laboratory of Chemistry of Northwestern Plant Resources, CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China 2.University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China 3.Key Laboratory of Oil & Gas Production, China National Petroleum Corporation (CNPC) and Research Institute of Petroleum Exploration and Development (RIPED), Beijing 100083, China |
| 推荐引用方式 GB/T 7714 | Tang S,Guo Y,Liang XJ,et al. Preparation and application of a novel mixed-mode monolith for reversed-phase and per aqueous capillary electrochromatography[J]. Analytical Methods,2015,7(11):4750-4756. |
| APA | Tang S.,Guo Y.,Liang XJ.,Wei, Falin.,Yang, Limin.,...&刘霞.(2015).Preparation and application of a novel mixed-mode monolith for reversed-phase and per aqueous capillary electrochromatography.Analytical Methods,7(11),4750-4756. |
| MLA | Tang S,et al."Preparation and application of a novel mixed-mode monolith for reversed-phase and per aqueous capillary electrochromatography".Analytical Methods 7.11(2015):4750-4756. |
入库方式： OAI收割
来源：兰州化学物理研究所
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