An NBD-based Fluorescent Probe with High Selectivity to Cysteine over Homocysteine under Neutral Physiological Conditions
文献类型：期刊论文
| 作者 | Wang JM(王佳敏)1,2,3 ; Liao Y(廖原)1,2,3; Shao SJ(邵士俊)1,2
|
| 刊名 | Chemistry Letters
 |
| 出版日期 | 2015 |
| 卷号 | 44期号:10页码:1437-1439 |
| ISSN号 | 0366-7022 |
| 英文摘要 | 7-nitro-2,1,3-benzoxadiazole (NBD)-based fluorescent probe for the detection of cysteine (Cys) over homocysteine (Hcy) and amino acids under neutral physiological conditions based on thiol-induced aromatic nucleophilic substitution reaction was synthesized by the reaction of 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) with p-thiocresol. The proposed sensing mechanism was proved by mass spectrometry of the reaction mixtures. This probe was successfully applied to the fluorescence imaging of Cys in HeLa cells. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000362622700054 |
| 源URL | [http://210.77.64.217/handle/362003/18722]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang JM,Liao Y,Shao SJ. An NBD-based Fluorescent Probe with High Selectivity to Cysteine over Homocysteine under Neutral Physiological Conditions[J]. Chemistry Letters,2015,44(10):1437-1439. |
| APA | Wang JM,Liao Y,&Shao SJ.(2015).An NBD-based Fluorescent Probe with High Selectivity to Cysteine over Homocysteine under Neutral Physiological Conditions.Chemistry Letters,44(10),1437-1439. |
| MLA | Wang JM,et al."An NBD-based Fluorescent Probe with High Selectivity to Cysteine over Homocysteine under Neutral Physiological Conditions".Chemistry Letters 44.10(2015):1437-1439. |
入库方式： OAI收割
来源：兰州化学物理研究所
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