Novel approach to improve the detection of colchicine via on–line coupling of ionic liquid–based single–drop microextraction with capillary electrophoresis
文献类型：期刊论文
| 作者 | Wang Q(王庆)1,2 ; Qiu HD(邱洪灯)1; Jing Li1,2; Han HF(韩海峰)1,2; Liu X(刘霞)1; Jiang SX(蒋生祥)1; Jiang SX(蒋生祥)
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| 刊名 | Journal of Separation Science
 |
| 出版日期 | 2011 |
| 卷号 | 34页码:594-600 |
| 关键词 | Capillary electrophoresis Colchicine Ionic liquid Online coupling Single-drop microextraction |
| ISSN号 | 1615-9306 |
| 通讯作者 | 蒋生祥 |
| 英文摘要 | A novel approach based on ionic liquid-single-drop microextraction (IL-SDME) online coupling with capillary electrophoresis (CE) was used to determine a toxic alkaloid – colchicine. The IL-SDME procedure was optimized by extraction solvent, drop volume controlling, sample volume and pH, extraction time, and ionic strength. Under optimum conditions, enrichment factor was as much as 41-fold with a relative standard deviation of 2.8% (n53). Linear range of response was observed from 1 to 100 μg/mL, with detection limit of 0.25 μg/mL and correlation coefficient (R2) of 0.9994. The extraction of colchicines from spiked Lanzhou lily sample was performed and obtaining good result with an average recovery rate of 102.4 and 98.8% at 5 and 50 μg/mL, respectively. Comparing with the previous methods, IL-SDME-CE is really a convenient, economical, and environmentally benign way for determining colchicine. |
| 学科主题 | 分析化学与药物化学 |
| 资助信息 | the National Natural Science Foundation of China (Grant Nos. 20905073;20905072;20975105);the Technology R&D Program of Gansu Province of China (0804GKCA034);Western Doctor |
| 语种 | 英语 |
| 源URL | [http://210.77.64.217/handle/362003/18886]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Jiang SX(蒋生祥) |
| 作者单位 | 1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P. R. China 2.Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, P. R. China |
| 推荐引用方式 GB/T 7714 | Wang Q,Qiu HD,Jing Li,et al. Novel approach to improve the detection of colchicine via on–line coupling of ionic liquid–based single–drop microextraction with capillary electrophoresis[J]. Journal of Separation Science,2011,34:594-600. |
| APA | Wang Q.,Qiu HD.,Jing Li.,Han HF.,Liu X.,...&蒋生祥.(2011).Novel approach to improve the detection of colchicine via on–line coupling of ionic liquid–based single–drop microextraction with capillary electrophoresis.Journal of Separation Science,34,594-600. |
| MLA | Wang Q,et al."Novel approach to improve the detection of colchicine via on–line coupling of ionic liquid–based single–drop microextraction with capillary electrophoresis".Journal of Separation Science 34(2011):594-600. |
入库方式： OAI收割
来源：兰州化学物理研究所
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