Graphene Oxide-Assisted Nucleic Acids Assays Using Conjugated Polyelectrolytes-Based Fluorescent Signal Transduction
文献类型：期刊论文
| 作者 | Li, F; Chao, J; Li, ZH; Xing, S; Su, S; Li, XX; Song, SP; Zuo, XL; Fan, CH; Liu, B |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2015 |
| 卷号 | 87期号:7页码:3877—3883 |
| 关键词 | POLYMER COMPLEXES DNA CANCER MICRORNAS ADSORPTION BIOMARKERS BIOSENSORS PROTEINS BINDING CELLS |
| 英文摘要 | In this work, we investigated the interactions between graphene oxide (GO) and conjugated polyelectrolytes (CPEs) with different backbone and side chain structures. By studying the mechanism of fluorescence quenching of CPEs by GO, we find that the charge and the molecular structure of CPEs play important roles for GO-CPEs interactions. Among them, electrostatic interaction, pi-pi interaction, and cation-pi bonding are dominant driving forces. By using a cationic P2, we have developed a sensitive homogeneous sensor for DNA and RNA detection with a detection limit of 50 pM DNA and RNA, which increased the sensitivity by 40-fold as compared to GO-free CPE-based sensors. This GO-assisted CPE sensing strategy is also generic and shows a high potential for biosensor designs based on aptamers, proteins, peptides, and other biological probes |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/24465]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Li, F,Chao, J,Li, ZH,et al. Graphene Oxide-Assisted Nucleic Acids Assays Using Conjugated Polyelectrolytes-Based Fluorescent Signal Transduction[J]. ANALYTICAL CHEMISTRY,2015,87(7):3877—3883. |
| APA | Li, F.,Chao, J.,Li, ZH.,Xing, S.,Su, S.,...&Wang, LH.(2015).Graphene Oxide-Assisted Nucleic Acids Assays Using Conjugated Polyelectrolytes-Based Fluorescent Signal Transduction.ANALYTICAL CHEMISTRY,87(7),3877—3883. |
| MLA | Li, F,et al."Graphene Oxide-Assisted Nucleic Acids Assays Using Conjugated Polyelectrolytes-Based Fluorescent Signal Transduction".ANALYTICAL CHEMISTRY 87.7(2015):3877—3883. |
入库方式： OAI收割
来源：上海应用物理研究所
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