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Regional homogeneity approach to fMRI data analysis

文献类型:期刊论文

作者Zang, YF; Jiang, TZ; Lu, YL; He, Y; Tian, LX
刊名NEUROIMAGE
出版日期2004-05-01
卷号22期号:1页码:394-400
关键词fMRI Kendall's coefficient concordance motor cortex general linear model
英文摘要Kendall's coefficient concordance (KCC) can measure the similarity of a number of time series. It has been used for purifying a given cluster in functional MRI (fMRI). In the present study, a new method was developed based on the regional homogeneity (ReHo), in which KCC was used to measure the similarity of the time series of a given voxel to those of its nearest neighbors in a voxel-wise way. Six healthy subjects performed left and right finger movement tasks in event-related design five of them were additionally scanned in a rest condition. KCC was compared among the three conditions (left finger movement, right finger movement, and the rest). Results show that bilateral primary motor cortex (M1) had higher KCC in either left or right finger movement condition than in rest condition. Contrary to prediction and to activation pattern, KCC of ipsilateral M1 is significantly higher than contralateral M1 in unilateral finger movement conditions. These results support the previous electrophysiologic findings of increasing ipsilateral M1 excitation during unilateral movement. ReHo can consider as a complementary method to model-driven method, and it could help reveal the complexity of the human brain function. More work is needed to understand the neural mechanism underlying ReHo. (C) 2004 Elsevier Inc. All rights reserved.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]FUNCTIONAL MRI DATA ; MOTOR CORTEX ; DEFAULT MODE ; ACTIVATION ; BRAIN ; MOVEMENTS ; SENSORIMOTOR ; CONNECTIVITY ; COMPONENTS ; DECREASES
收录类别SCI
语种英语
WOS记录号WOS:000221190200041
公开日期2015-12-24
源URL[http://ir.ia.ac.cn/handle/173211/8923]  
专题自动化研究所_09年以前成果
作者单位1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Key Lab Mental Hlth, Beijing 100101, Peoples R China
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Zang, YF,Jiang, TZ,Lu, YL,et al. Regional homogeneity approach to fMRI data analysis[J]. NEUROIMAGE,2004,22(1):394-400.
APA Zang, YF,Jiang, TZ,Lu, YL,He, Y,&Tian, LX.(2004).Regional homogeneity approach to fMRI data analysis.NEUROIMAGE,22(1),394-400.
MLA Zang, YF,et al."Regional homogeneity approach to fMRI data analysis".NEUROIMAGE 22.1(2004):394-400.

入库方式: OAI收割

来源:自动化研究所

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