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Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging
文献类型：期刊论文
| 作者 | Liang, M ; Zhou, Y; Jiang, TZ; Liu, ZN; Tian, LX; Liu, HH; Hao, YH
|
| 刊名 | NEUROREPORT
 |
| 出版日期 | 2006-02-06 |
| 卷号 | 17期号:2页码:209-213 |
| 关键词 | functional connectivity functional magnetic resonance imaging resting state schizophrenia |
| 英文摘要 | Using resting-state functional magnetic resonance imaging, we examined the functional connectivity throughout the entire brain in schizophrenia. The abnormalities in functional connectivity were identified by comparing the correlation coefficients of each pair of 116 brain regions between 15 patients and 15 controls. Then, the global distribution of the abnormal functional connectivities was examined. Experimental results indicated, in general, a decreased functional connectivity in schizophrenia during rest, and such abnormalities were widely distributed throughout the entire brain rather than restricted to a few specific brain regions. The results provide a quantitative support for the hypothesis that schizophrenia may arise from the disrupted functional integration of widespread brain areas. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | HUMAN BRAIN ; 1ST-EPISODE SCHIZOPHRENIA ; MOTOR CORTEX ; CONNECTIVITY ; IMAGES ; FMRI ; MRI ; FLUCTUATIONS ; SINGLE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000235349800020 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/9232]  |
| 专题 | 自动化研究所_09年以前成果 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China 2.Cent S Univ, Xiangya Hosp 2, Inst Mental Hlth, Changsha 410083, Hunan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liang, M,Zhou, Y,Jiang, TZ,et al. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging[J]. NEUROREPORT,2006,17(2):209-213. |
| APA | Liang, M.,Zhou, Y.,Jiang, TZ.,Liu, ZN.,Tian, LX.,...&Hao, YH.(2006).Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging.NEUROREPORT,17(2),209-213. |
| MLA | Liang, M,et al."Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging".NEUROREPORT 17.2(2006):209-213. |
入库方式： OAI收割
来源：自动化研究所
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