Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD
文献类型：期刊论文
| 作者 | Hou, Cailan; Liu, Jun; Wang, Kun; Li, Lingjiang; Liang, Meng; He, Zhong; Liu, Yong ; Zhang, Yan; Li, Weihui; Jiang, Tianzi
|
| 刊名 | BRAIN RESEARCH
 |
| 出版日期 | 2007-05-04 |
| 卷号 | 1144页码:165-174 |
| 关键词 | coal mining accident acute severe PTSD fMRI |
| 英文摘要 | Functional neuroimaging studies have largely been performed in patients with longstanding chronic posttraumatic stress disorder (PTSD). Additionally, memory function of PTSD patients has been proved to be impaired. We sought to characterize the brain responses of patients with acute PTSD and implemented a trauma-related short-term memory recall paradigm. Individuals with acute severe PTSD (n = 10) resulting from a mining accident and 7 men exposed to the mining accident without PTSD underwent functional magnetic resonance imaging (fMRI) while performing the symptom provocation and trauma-related short-term memory recall paradigms. During symptom provocation paradigm, PTSD subjects showed diminished responses in right anterior cingulate gyrus, left inferior frontal gyrus and bilateral middle frontal gyrus and enhanced left parahippocampal. gyrus response compared with controls. During the short-term memory recall paradigm, PTSD group showed diminished responses in right inferior frontal gyrus, right middle frontal and left middle occipital gyrus in comparison with controls. PTSD group exhibited diminished right parahippocampal gyrus response during the memory recall task as compared to the symptom provocation task. Our findings suggest that neurophysiological alterations and memory performance deficit have developed in acute severe PTSD. (c) 2007 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | POSTTRAUMATIC-STRESS-DISORDER ; MEDIAL PREFRONTAL CORTEX ; ANTERIOR CINGULATE CORTEX ; CHILDHOOD SEXUAL-ABUSE ; SCRIPT-DRIVEN IMAGERY ; POSITRON-EMISSION-TOMOGRAPHY ; CEREBRAL-BLOOD-FLOW ; FUNCTIONAL MRI ; HIPPOCAMPAL VOLUME ; AMYGDALA RESPONSE |
| 收录类别 | SCI ; SSCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000246034100019 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/9388]  |
| 专题 | 自动化研究所_09年以前成果 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Med Imaging & Cop Natl Lab, Beijing 100080, Peoples R China 2.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha 410011, Hunan, Peoples R China 3.Cent S Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Cailan,Liu, Jun,Wang, Kun,et al. Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD[J]. BRAIN RESEARCH,2007,1144:165-174. |
| APA | Hou, Cailan.,Liu, Jun.,Wang, Kun.,Li, Lingjiang.,Liang, Meng.,...&Jiang, Tianzi.(2007).Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD.BRAIN RESEARCH,1144,165-174. |
| MLA | Hou, Cailan,et al."Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD".BRAIN RESEARCH 1144(2007):165-174. |
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来源：自动化研究所
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