中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Alignment of two-dimensional electrophoresis gels

文献类型:期刊论文

作者Shi, Guihua; Jiang, Tianzi; Zhu, Wanlin; Liu, Bing; Zhao, Huizhi
刊名BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
出版日期2007-06-01
卷号357期号:2页码:427-432
关键词2D-gel electrophoresis image image alignment ICP algorithm informational potential
英文摘要Two-dimensional electrophoresis is a major separating technique for proteins in proteomics. Alignment of gel images is critical for intra-laboratory or even more difficult inter-laboratory gel comparisons. In the paper, we propose a novel iterative closest point (ICP) method for 2D-gel electrophoresis image alignment. The paper seeks to introduce an information theoretic measure as one part of distance metric to gel image alignment. We combine intensity information of spots with geometric information of landmarks by applying information potential idea. The proposed method has been applied to both synthetic and real gel images accessible in public 2D-electrophoresis gel protein databases. The high accuracy and robustness of the algorithm indicate that it is promising for gel image alignment. (c) 2007 Elsevier Inc. All rights reserved.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]ELASTIC REGISTRATION ; IMAGE REGISTRATION ; INFORMATION
收录类别SCI
语种英语
WOS记录号WOS:000246253700017
公开日期2015-12-24
源URL[http://ir.ia.ac.cn/handle/173211/9423]  
专题自动化研究所_09年以前成果
作者单位Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Shi, Guihua,Jiang, Tianzi,Zhu, Wanlin,et al. Alignment of two-dimensional electrophoresis gels[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2007,357(2):427-432.
APA Shi, Guihua,Jiang, Tianzi,Zhu, Wanlin,Liu, Bing,&Zhao, Huizhi.(2007).Alignment of two-dimensional electrophoresis gels.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,357(2),427-432.
MLA Shi, Guihua,et al."Alignment of two-dimensional electrophoresis gels".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 357.2(2007):427-432.

入库方式: OAI收割

来源:自动化研究所

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