Structural and functional deficits in human amblyopia
文献类型：期刊论文
| 作者 | Lv, Bin1; He, Huiguang1 ; Li, Xingfeng3; Zhang, Zhiqiang2; Huang, Wei2; Li, Meng1; Lu, Guangming2
|
| 刊名 | NEUROSCIENCE LETTERS
 |
| 出版日期 | 2008-05-23 |
| 卷号 | 437期号:1页码:5-9 |
| 关键词 | amblyopia cortical thickness visual cortex retinotopic fMRI |
| 英文摘要 | Many neuroimaging tools have been used to assess the site of the cortical deficits in human amblyopia. In this paper, we aimed at detecting the structural and functional deficits in humans with amblyopia, with the aid of anatomic magnetic resonance imaging (aMRI) and functional MRI (fMRI). We designed the visual stimulus to investigate the functional deficits, and delineated the V1/V2 areas by retinotopic mapping. Then we performed the brain parcellation to calculate the volume of the subcortical structure on each individual, and reconstructed the cortical surfaces to measure the cortical thickness. At last, the statistical comparison was carried out to find the structural abnormities and their relationship to the functional deficits. Compared with the normal controls, it is found that the hemisphere difference existed on the unilateral amblyopia subjects, and the functional deficit might come along with the changes in the cortical volume, especially in the occipital lobe. The examined results may provide insight to the study of the neural substrates of amblyopia. Crown Copyright (C) 2008 Published by Elsevier Ireland Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | VOXEL-BASED MORPHOMETRY ; ABNORMAL VISUAL-CORTEX ; STRABISMIC AMBLYOPIA ; CORTICAL THICKNESS ; MRI DATA ; CONTRAST ; ADULTS ; AREAS ; FMRI ; ACTIVATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000256201000002 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/9540]  |
| 专题 | 自动化研究所_09年以前成果 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Complex Syst & Intelligence Sci, Inst Automat, Beijing 100190, Peoples R China 2.Nanjing Univ, Dept Med Imaging, Nanjing Jinling Hosp, Nanjing 21002, Peoples R China 3.McGill Univ, McGill Vis Res, Dept Ophthalmol, Montreal, PQ H3A 1A1, Canada |
| 推荐引用方式 GB/T 7714 | Lv, Bin,He, Huiguang,Li, Xingfeng,et al. Structural and functional deficits in human amblyopia[J]. NEUROSCIENCE LETTERS,2008,437(1):5-9. |
| APA | Lv, Bin.,He, Huiguang.,Li, Xingfeng.,Zhang, Zhiqiang.,Huang, Wei.,...&Lu, Guangming.(2008).Structural and functional deficits in human amblyopia.NEUROSCIENCE LETTERS,437(1),5-9. |
| MLA | Lv, Bin,et al."Structural and functional deficits in human amblyopia".NEUROSCIENCE LETTERS 437.1(2008):5-9. |
入库方式： OAI收割
来源：自动化研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。