An optimal permissible source region strategy for multispectral bioluminescence tomography
文献类型：期刊论文
| 作者 | Feng, Jinchao1; Jia, Kebin1; Yan, Guorui2; Zhu, Shouping2; Qin, Chenghu2; Lv, Yujie2; Tian, Jie2,3
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| 刊名 | OPTICS EXPRESS
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| 出版日期 | 2008-09-29 |
| 卷号 | 16期号:20页码:15640-15654 |
| 关键词 | Tomography Image reconstruction techniques Light propagation in tissues Spectroscopy fluorescence luminescence |
| 通讯作者 | Tian, Jie |
| 英文摘要 | Multispectral bioluminescence tomography (BLT) attracts increasing more attention in the area of small animal studies because multispectral data acquisition could help in the 3D location of bioluminescent sources. Generally, BLT problem is ill-posed and a priori information is indispensable to reconstruction bioluminescent source uniquely and quantitatively. In this paper, we propose a spectrally solved bioluminescence tomography algorithm with an optimal permissible source region strategy. Being the most different from earlier studies, an optimal permissible source region strategy which is automatically selected without human intervention is developed to reduce the ill-posedness of BLT and therefore improves the reconstruction quality. Furthermore, both numerical stability and computational efficiency benefit from the strategy. In the numerical experiments, a heterogeneous phantom is used to evaluate the proposed algorithm and the synthetic data is produced by Monte Carlo method for avoiding the inverse crime. The results demonstrate the feasibility and potential of our methodology for reconstructing the distribution of bioluminescent sources. (C) 2008 Optical Society of America |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Optics |
| 研究领域[WOS] | Optics |
| 关键词[WOS] | OPTICAL TOMOGRAPHY ; RECONSTRUCTION METHOD ; SIMULATION ; LIGHT ; MOUSE ; MEDIA |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000260091300038 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/9621]  |
| 专题 | 自动化研究所_09年以前成果 |
| 作者单位 | 1.Beijing Univ Technol, Coll Elect Informat & Control Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100190, Peoples R China 3.Xidian Univ, Life Sci Res Ctr, Xian 710071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Jinchao,Jia, Kebin,Yan, Guorui,et al. An optimal permissible source region strategy for multispectral bioluminescence tomography[J]. OPTICS EXPRESS,2008,16(20):15640-15654. |
| APA | Feng, Jinchao.,Jia, Kebin.,Yan, Guorui.,Zhu, Shouping.,Qin, Chenghu.,...&Tian, Jie.(2008).An optimal permissible source region strategy for multispectral bioluminescence tomography.OPTICS EXPRESS,16(20),15640-15654. |
| MLA | Feng, Jinchao,et al."An optimal permissible source region strategy for multispectral bioluminescence tomography".OPTICS EXPRESS 16.20(2008):15640-15654. |
入库方式： OAI收割
来源：自动化研究所
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