中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study

文献类型:期刊论文

作者Gong, Gaolang1; Shi, Feng3; Concha, Luis1; Beaulieu, Christian1; Gross, Donald W.2
刊名EPILEPSIA
出版日期2008-11-01
卷号49期号:11页码:1941-1945
关键词Status epilepticus Hippocampus Fornix
英文摘要While acute hippocampal magnetic resonance imaging (MRI) changes have been demonstrated, the long-term structural consequence of status epilepticus remains unclear. Also the timing of previously reported fornix abnormalities in patients with mesial temporal sclerosis (MTS) is unknown. We report longitudinal volumetic MRI and diffusion tensor imaging (DTI) findings of the hippocampus and fornix in a patient following status epilepticus. Left hippocampal atrophy demonstrated progression beyond 6 months poststatus epilepticus while the right hippocampus and bilateral fornices demonstrated stable volumetric and diffusion abnormalities throughout the study. Our findings provide evidence that status epilepticus can induce permanent hippocampal damage with the delayed timing of the structural changes being consistent with programmed cell death.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Clinical Neurology
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]GENERALIZED STATUS EPILEPTICUS ; EPILEPSY ; ABNORMALITIES ; EVOLUTION ; DAMAGE
收录类别SCI
语种英语
WOS记录号WOS:000260744200012
公开日期2015-12-24
源URL[http://ir.ia.ac.cn/handle/173211/9627]  
专题自动化研究所_09年以前成果
作者单位1.Univ Alberta, Dept Biomed Engn, Edmonton, AB, Canada
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100864, Peoples R China
3.Univ Alberta, Dept Med, Div Neurol, Edmonton, AB, Canada
推荐引用方式
GB/T 7714
Gong, Gaolang,Shi, Feng,Concha, Luis,et al. Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study[J]. EPILEPSIA,2008,49(11):1941-1945.
APA Gong, Gaolang,Shi, Feng,Concha, Luis,Beaulieu, Christian,&Gross, Donald W..(2008).Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study.EPILEPSIA,49(11),1941-1945.
MLA Gong, Gaolang,et al."Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study".EPILEPSIA 49.11(2008):1941-1945.

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来源:自动化研究所

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