DISCRIMINATIVE ANALYSIS OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY SIGNALS FOR DEVELOPMENT OF NEUROIMAGING BIOMARKERS OF ELDERLY DEPRESSION
文献类型：期刊论文
| 作者 | Zhu, Ye1; Jiang, Tianzi1 ; Zhou, Yuan1; Zhao, Lisha2
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| 刊名 | JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES
 |
| 出版日期 | 2010 |
| 卷号 | 3期号:1页码:69-74 |
| 关键词 | Functional near-infrared spectroscopy (fNIRS) Fisher linear discriminant analysis (FLDA) depression |
| 英文摘要 | Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technology which is suitable for psychiatric patients. Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depression. In this paper, we proposed a discriminative model of multivariate pattern classification based on fNIRS signals to distinguish elderly depressed patients from healthy controls. This model used the brain activation patterns during a verbal fluency task as features of classification. Then Pseudo-Fisher Linear Discriminant Analysis was performed on the feature space to generate discriminative model. Using leave-one-out (LOO) cross-validation, our results showed a correct classification rate of 88%. The discriminative model showed its ability to identify people with elderly depression and suggested that fNIRS may be an efficient clinical tool for diagnosis of depression. This study may provide the first step for the development of neuroimaging biomarkers based on fNIRS in psychiatric disorders. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine |
| 类目[WOS] | Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 研究领域[WOS] | Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000208647600010 |
| 公开日期 | 2015-12-24 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/9945]  |
| 专题 | 自动化研究所_脑网络组研究中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China 2.Capital Univ Med Sci, Beijing Anding Hosp, Beijing 100088, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Ye,Jiang, Tianzi,Zhou, Yuan,et al. DISCRIMINATIVE ANALYSIS OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY SIGNALS FOR DEVELOPMENT OF NEUROIMAGING BIOMARKERS OF ELDERLY DEPRESSION[J]. JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES,2010,3(1):69-74. |
| APA | Zhu, Ye,Jiang, Tianzi,Zhou, Yuan,&Zhao, Lisha.(2010).DISCRIMINATIVE ANALYSIS OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY SIGNALS FOR DEVELOPMENT OF NEUROIMAGING BIOMARKERS OF ELDERLY DEPRESSION.JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES,3(1),69-74. |
| MLA | Zhu, Ye,et al."DISCRIMINATIVE ANALYSIS OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY SIGNALS FOR DEVELOPMENT OF NEUROIMAGING BIOMARKERS OF ELDERLY DEPRESSION".JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES 3.1(2010):69-74. |
入库方式： OAI收割
来源：自动化研究所
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