Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice (SCI)
文献类型:期刊论文
作者 | Sun Y. X. ; Liu T. ; Dai X. L. ; Li Y. B. ; Li Y. Y. ; Zhang H. ; An L. Z. |
刊名 | Journal of Chemistry |
出版日期 | 2014 |
卷号 | 9 |
英文摘要 | The purpose of the present study was to clarify whether the water extract of Chorispora bungeana was an antioxidant agent against cerebral ischemia/reperfusion (I/R). Our results showed that water extract of Chorispora bungeana treatment significantly reduced neurological deficit scores, infarct size, MDA and carbonyl contents, and GSH/GSSG ratio compared with the model control group. After being treated by Chorispora bungeana, SOD, CAT, and GSH-Px activities remarkably increased. Chorispora bungeana treatment also improved 8-OHdG expression and cell apoptosis. Our findings indicated that the water extract of Chorispora bungeana possesses neuroprotective effect which is most likely achieved by antioxidant and antiapoptotic activities. |
收录类别 | SCI |
公开日期 | 2015-12-24 |
源URL | [http://ir.casnw.net/handle/362004/25164] |
专题 | 寒区旱区环境与工程研究所_中科院寒区旱区环境与工程研究所(未分类)_期刊论文 |
推荐引用方式 GB/T 7714 | Sun Y. X.,Liu T.,Dai X. L.,et al. Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice (SCI)[J]. Journal of Chemistry,2014,9. |
APA | Sun Y. X..,Liu T..,Dai X. L..,Li Y. B..,Li Y. Y..,...&An L. Z..(2014).Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice (SCI).Journal of Chemistry,9. |
MLA | Sun Y. X.,et al."Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice (SCI)".Journal of Chemistry 9(2014). |
入库方式: OAI收割
来源:寒区旱区环境与工程研究所
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