Development of a New Risk Score for Incident Type 2 Diabetes Using Updated Diagnostic Criteria in Middle-Aged and Older Chinese
文献类型：期刊论文
| 作者 | Ye, Xingwang; Zong, Geng; Liu, Xin; Liu, Gang; Gan, Wei; Zhu, Jingwen; Lu, Ling; Sun, Liang（孙亮）; Li, Huaixing（黎怀星）; Hu, Frank B. |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2014 |
| 卷号 | 9期号:5页码:e97042 |
| 通讯作者 | Lin, X (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Nutr & Metab, Shanghai, Peoples R China. |
| 英文摘要 | Type 2 diabetes mellitus (T2DM) reaches an epidemic proportion among adults in China. However, no simple score has been created for the prediction of T2DM incidence diagnosed by updated criteria with hemoglobin A1c (HbA1c) >= 6.5% included in Chinese. In a 6-year follow-up cohort in Beijing and Shanghai, China, we recruited a total of 2529 adults aged 50-70 years in 2005 and followed them up in 2011. Fasting plasma glucose (FPG), HbA1c, and C-reactive protein (CRP) were measured and incident diabetes was identified by the recently updated criteria. Of the 1912 participants without T2DM at baseline, 924 were identified as having T2DM at follow-up, and most of them (72.4%) were diagnosed using the HbA1c criterion. Baseline body mass index, FPG, HbA1c, CRP, hypertension, and female gender were all significantly associated with incident T2DM. Based upon these risk factors, a simple score was developed with an estimated area under the receiver operating characteristic curve of 0.714 (95% confidence interval: 0.691, 0.737), which performed better than most of existing risk score models developed for eastern Asian populations. This simple, newly constructed score of six parameters may be useful in predicting T2DM in middle-aged and older Chinese. |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | C-REACTIVE PROTEIN ; HEALTH MANAGEMENT CENTER ; A1C-BASED DIAGNOSIS ; PREVALENCE ; RETINOPATHY ; HEMOGLOBIN ; JAPAN ; RECLASSIFICATION ; ASSOCIATION ; POPULATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000336653300064 |
| 公开日期 | 2015-12-24 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/185]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_人类营养与疾病研究组 |
| 推荐引用方式 GB/T 7714 | Ye, Xingwang,Zong, Geng,Liu, Xin,et al. Development of a New Risk Score for Incident Type 2 Diabetes Using Updated Diagnostic Criteria in Middle-Aged and Older Chinese[J]. PLOS ONE,2014,9(5):e97042. |
| APA | Ye, Xingwang.,Zong, Geng.,Liu, Xin.,Liu, Gang.,Gan, Wei.,...&Lin, Xu.(2014).Development of a New Risk Score for Incident Type 2 Diabetes Using Updated Diagnostic Criteria in Middle-Aged and Older Chinese.PLOS ONE,9(5),e97042. |
| MLA | Ye, Xingwang,et al."Development of a New Risk Score for Incident Type 2 Diabetes Using Updated Diagnostic Criteria in Middle-Aged and Older Chinese".PLOS ONE 9.5(2014):e97042. |
入库方式： OAI收割
来源：上海营养与健康研究所
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