Hypertriglyceridemic waist, cytokines and hyperglycaemia in Chinese
文献类型：期刊论文
| 作者 | Yu, Zhijie; Sun, Liang（孙亮）; Qi, Qibin; Wu, Hongyu; Lu, Ling; Liu, Chen; Li, Huaixing（黎怀星）; Lin, Xu（林旭）
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| 刊名 | EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
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| 出版日期 | 2012 |
| 卷号 | 42期号:10页码:1100-1111 |
| 关键词 | adipokines hyperglycaemia hypertriglyceridemic waist inflammatory factors |
| 通讯作者 | Yu, ZJ (reprint author), Chinese Acad Sci, Inst Nutr Sci, Shanghai Inst Biol Sci, Key Lab Nutr & Metab, 294 Tai Yuan Rd, Shanghai 200031, Peoples R China. |
| 英文摘要 | Eur J Clin Invest 2012; 42 (10): 11001111 Abstract Background Abdominal obesity and hypertriglyceridemia confer high risk for cardiometabolic disease. Few studies have investigated the associations of hypertriglyceridemic waist with cytokines and hyperglycaemia in Chinese. Methods Anthropometric indexes, fasting plasma concentrations of glucose, glycohemoglobin, insulin, lipid profile, inflammatory factors and adipokines were measured among 3289 Chinese men and women 5070 years of age. Results An increment of every 2 cm of waist circumference was associated with increased levels of high-sensitive C-reactive protein (hsCRP), interleukin 6 and RBP 4 by 0.033 mg/L, 0.018 ng/L and 0.556 mg/L and reduced levels of adiponectin by 0.269 mg/L (all P < 0.05), respectively, with controlling for potential confounders. For triglycerides, each an increment of 20 mg/dL was associated with increased levels of hsCRP, RBP4, and decreased levels of adiponectin by 0.021 mg/L, 0.655 mg/L, and 0.371 mg/L (all P < 0.05), respectively. Individuals with hypertriglyceridemic waist had increased risks of having hyperglycaemia (OR: 1.48; 95% CI: 1.09, 2.00) and diabetes mellitus (OR: 2.12; 95% CI: 1.47, 3.04) compared with those with neither of the phenotypes. Conclusions Hypertriglyceridemic waist is associated with a worse profile of inflammatory factors and adipokines as well as with an increased risk of having hyperglycaemia among Chinese. |
| 类目[WOS] | Medicine, General & Internal ; Medicine, Research & Experimental |
| 研究领域[WOS] | General & Internal Medicine ; Research & Experimental Medicine |
| 关键词[WOS] | ATHEROGENIC METABOLIC TRIAD ; C-REACTIVE PROTEIN ; BODY-MASS INDEX ; ABDOMINAL ADIPOSITY ; INFLAMMATORY FACTORS ; INSULIN-RESISTANCE ; PHYSICAL-ACTIVITY ; ENLARGED WAIST ; OBESITY ; RISK |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000308713400009 |
| 公开日期 | 2015-12-24 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/199]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_人类营养与疾病研究组 |
| 推荐引用方式 GB/T 7714 | Yu, Zhijie,Sun, Liang,Qi, Qibin,et al. Hypertriglyceridemic waist, cytokines and hyperglycaemia in Chinese[J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION,2012,42(10):1100-1111. |
| APA | Yu, Zhijie.,Sun, Liang.,Qi, Qibin.,Wu, Hongyu.,Lu, Ling.,...&Lin, Xu.(2012).Hypertriglyceridemic waist, cytokines and hyperglycaemia in Chinese.EUROPEAN JOURNAL OF CLINICAL INVESTIGATION,42(10),1100-1111. |
| MLA | Yu, Zhijie,et al."Hypertriglyceridemic waist, cytokines and hyperglycaemia in Chinese".EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 42.10(2012):1100-1111. |
入库方式： OAI收割
来源：上海营养与健康研究所
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