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Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese
文献类型：期刊论文
| 作者 | Pan, An; Lu, Ling; Franco, Oscar H.; Yu, Zhijie; Li, Huaixing（黎怀星）; Lin, Xu（林旭）
|
| 刊名 | JOURNAL OF AFFECTIVE DISORDERS
 |
| 出版日期 | 2009 |
| 卷号 | 118期号:1-3页码:240-243 |
| 关键词 | Depression 25-hydroxyvitamin D Chinese Cross-sectional study |
| 通讯作者 | Lin, X (reprint author), Chinese Acad Sci, Inst Nutr Sci, Shanghai Inst Biol Sci, Key Lab Nutr & Metab, 294 Tai Yuan Rd, Shanghai 200031, Peoples R China. |
| 英文摘要 | Background: Vitamin D deficiency is recently speculated to play a role in the development of depression, Nevertheless, few studies have explored the association between blood 25-hydroxyvitamin D [25(OH)D] concentrations and depression in the general population. Therefore, we aimed to determine this association in middle-aged and elderly Chinese. Methods: We conducted a population-based cross-sectional study in 2005 in Beijing and Shanghai, China. Participants included 3262 Community residents aged 50-70. Depressive symptoms were defined as a Center for Epidemiological Studies of Depression Scale (CES-D) score of 16 or higher.. Circulating 25(OH)D concentrations were measured by radioimmumoassay. Results: The prevalence of depressive symptoms was lower in the top fertile of 25(OH)D concentrations compared to the lowest tertile (7.2% vs. 11.1%) in the study population (odds ratio, 0.62; 95% confidence interval, 0.46-0.83; P for trend= 0.002). This association was substantially attenuated after controlling for various confounding factors, and disappeared after including geographic location in the model. Stratified analysis by location did not find any association between depressive symptoms and 25(OH)D levels among participants from either Beijing or Shanghai. Limitations: Due to the cross-sectional study design, causal relation remains unknown. Conclusions: Depressive symptoms are not associated with 25(OH)D concentrations in middle-aged and elderly Chinese. Further prospective Studies are required to determine whether they are correlated. (C) 2009 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Clinical Neurology ; Psychiatry |
| 研究领域[WOS] | Neurosciences & Neurology ; Psychiatry |
| 关键词[WOS] | VITAMIN-D DEFICIENCY ; PARATHYROID-HORMONE ; D SUPPLEMENTATION ; OLDER-ADULTS ; WINTER ; TRIAL ; MOOD |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000270750500035 |
| 公开日期 | 2015-12-24 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/224]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_人类营养与疾病研究组 |
| 推荐引用方式 GB/T 7714 | Pan, An,Lu, Ling,Franco, Oscar H.,et al. Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese[J]. JOURNAL OF AFFECTIVE DISORDERS,2009,118(1-3):240-243. |
| APA | Pan, An,Lu, Ling,Franco, Oscar H.,Yu, Zhijie,Li, Huaixing,&Lin, Xu.(2009).Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese.JOURNAL OF AFFECTIVE DISORDERS,118(1-3),240-243. |
| MLA | Pan, An,et al."Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese".JOURNAL OF AFFECTIVE DISORDERS 118.1-3(2009):240-243. |
入库方式： OAI收割
来源：上海营养与健康研究所
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