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Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People
文献类型：期刊论文
| 作者 | Yu, Zhijie; Ye, Xingwang; Wang, Jing; Qi, Qibin; Franco, Oscar H.; Rennie, Kirsten L.; Pan, An; Li, Huaixing（黎怀星）; Liu, Yong（刘勇） ; Hu, Frank B.
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| 刊名 | CIRCULATION
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| 出版日期 | 2009 |
| 卷号 | 119期号:23页码:2969 |
| 关键词 | adipocytokines cross-sectional studies exercise inflammation metabolic syndrome |
| 通讯作者 | Lin, X (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Nutr & Metab, 294 Tai Yuan Rd, Shanghai 200031, Peoples R China. |
| 英文摘要 | Background-Inflammatory factors, adipocytokines, and the metabolic syndrome are important determinants of cardiometabolic disease. It remains unclear how physical activity is related to these risk factors. Our objective was to investigate single and joint associations of physical activity with inflammatory factors, adipocytokines, and the metabolic syndrome among middle-aged and older Chinese people. Methods and Results-A total of 3289 individuals ( 1458 men, 1831 women) 50 to 70 years of age participated in a population-based cross-sectional survey in Beijing and Shanghai, China. Levels of total physical activity were assessed with the International Physical Activity Questionnaire. High-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-alpha receptor 2, adiponectin, and retinol-binding protein 4 were measured. The metabolic syndrome was defined using the updated National Cholesterol Education Program/Adult Treatment Panel III criteria for Asian Americans. Plasma concentrations of high-sensitivity C-reactive protein were 1.58, 1.74, and 1.27 mg/ L (P=0.0138) and of adiponectin were 16.12, 16.20, and 17.21 mg/ L (P=0.0078) among individuals with low, medium, and high levels of total physical activity, respectively, with adjustment for potential confounders. In the multivariable-adjusted logistic regression analyses, participants with higher levels of total physical activity had a lower risk of having the metabolic syndrome ( odds ratio, 0.68; 95% confidence interval, 0.54 to 0.85; P for trend=0.001) compared with those with lower levels. Conclusions-Being physically active is associated with a better profile of inflammatory factors and adipocytokines and a reduced risk of having the metabolic syndrome among Chinese people. ( Circulation. 2009; 119: 2969-2977.) |
| 类目[WOS] | Cardiac & Cardiovascular Systems ; Peripheral Vascular Disease |
| 研究领域[WOS] | Cardiovascular System & Cardiology |
| 关键词[WOS] | C-REACTIVE PROTEIN ; LIFE-STYLE INTERVENTION ; INSULIN-RESISTANCE ; CARDIOVASCULAR-DISEASE ; ADIPOSE-TISSUE ; PREVENTION ; CYTOKINES ; EXERCISE ; OBESITY ; RETINOL-BINDING-PROTEIN-4 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000267016900003 |
| 公开日期 | 2015-12-24 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/229]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_人类营养与疾病研究组 中国科学院上海生命科学研究院营养科学研究所_糖脂代谢与调控研究组 |
| 推荐引用方式 GB/T 7714 | Yu, Zhijie,Ye, Xingwang,Wang, Jing,et al. Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People[J]. CIRCULATION,2009,119(23):2969. |
| APA | Yu, Zhijie.,Ye, Xingwang.,Wang, Jing.,Qi, Qibin.,Franco, Oscar H..,...&Lin, Xu.(2009).Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People.CIRCULATION,119(23),2969. |
| MLA | Yu, Zhijie,et al."Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People".CIRCULATION 119.23(2009):2969. |
入库方式： OAI收割
来源：上海营养与健康研究所
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