A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity
文献类型：期刊论文
| 作者 | Zhang, Jian1; Lv, Yanlin1; Zhang, Wei2; Ding, Hui1; Liu, Rongji3; Zhao, Yongsheng2; Zhang, Guangjin3; Tian, Zhiyuan1 |
| 刊名 | TALANTA
 |
| 出版日期 | 2016 |
| 卷号 | 146期号:JAN页码:41-48 |
| 关键词 | Fluorescent probe Cysteine/homocysteine Bioimaging |
| ISSN号 | 0039-9140 |
| 英文摘要 | A new type of flavone-based fluorescent probe (DMAF) capable of cysteine (Cys)/homocysteine (Hcy) sensing with high selectivity over other amino acids was developed. Such type of probe undergoes Cys/Hcy-mediated cyclization reaction with the involvement of its aldehyde group, which suppresses of the photoinduced electron transfer (PET) process of the probe molecule and consequently leads to the enhancement of fluorescence emission upon excitation using visible light. The formation of product of the Cys/Hcy-mediated cyclization reaction was confirmed and the preliminary fluorescence imaging experiments revealed the biocompatibility of the as-prepared probe and validated its practicability for intracellular Cys/Hcy sensing. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Analytical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | TOTAL HOMOCYSTEINE ; LIVING CELLS ; CYSTEINE ; THIOLS ; MECHANISMS ; NEUROTOXICITY ; NANOCLUSTERS ; CHEMOSENSORS ; GLUTATHIONE ; ELECTRODE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000363815600007 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/19763]  |
| 专题 | 过程工程研究所_多相复杂系统国家重点实验室 |
| 作者单位 | 1.UCAS, Sch Chem & Chem Engn, Beijing 100049, PR, Peoples R China 2.Chinese Acad Sci, BNLMS, Inst Chem, Key Lab Photochem, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Key Lab Green Proc & Engn, Beijing Key Lab Ion Liquids Clean Proc, Inst Proc Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jian,Lv, Yanlin,Zhang, Wei,et al. A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity[J]. TALANTA,2016,146(JAN):41-48. |
| APA | Zhang, Jian.,Lv, Yanlin.,Zhang, Wei.,Ding, Hui.,Liu, Rongji.,...&Tian, Zhiyuan.(2016).A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity.TALANTA,146(JAN),41-48. |
| MLA | Zhang, Jian,et al."A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity".TALANTA 146.JAN(2016):41-48. |
入库方式： OAI收割
来源：过程工程研究所
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