Subcritical water extraction of betulinic acid from birch bark
文献类型：期刊论文
| 作者 | Liu, Jing1,2; Chen, Pan1; Yao, Wenjia1; Wang, Jia1; Wang, Luying1; Deng, Lihong1; He, Jing1; Zhang, Guifeng3; Lei, Jiandu1,2 |
| 刊名 | INDUSTRIAL CROPS AND PRODUCTS
 |
| 出版日期 | 2015-11-15 |
| 卷号 | 74期号:NOV页码:557-565 |
| 关键词 | Subcritical water extraction Betulinic acid Response surface methodology Modeling HPLC |
| ISSN号 | 0926-6690 |
| 英文摘要 | An alternative and green method for extraction of betulinic acid (BA) from birch bark is here proposed as Subcritical Water Extraction (SWE). Using response surface methodology (RSM), optimization was conducted on reaction parameters for maximum extraction yield of BA. Optimal modifying conditions are as follows: extraction time of 27.37 min, extraction temperature at 184.52 degrees C and a solvent/solid ratio of 59.60 mL/g. Under optimal conditions, the maximum BA yield was 28.03 mg/10 g birch bark. Extracts by different methods (leaching extraction, reflux extraction, ultrasonic extraction, and SWE) were comparatively and quantitatively analyzed, using High Performance Liquid Chromatography (HPLC). Results show BA yields by SWE are higher than those obtained using ethanol, a traditional extraction method, plus the extract contained fewer impurities. Furthermore, the extraction processes for all four of the above methods were modeled and reviewed individually. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Agricultural Engineering ; Agronomy |
| 研究领域[WOS] | Agriculture |
| 关键词[WOS] | RESPONSE-SURFACE METHODOLOGY ; ASSISTED EXTRACTION ; OLEANOLIC ACID ; OPTIMIZATION ; POLYSACCHARIDES ; INHIBITION ; MECHANISM ; DESIGN ; PHASE ; SEEDS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000360948900073 |
| 公开日期 | 2015-12-27 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/19532]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Beijing Forestry Univ, Beijing Key Lab Lignocellulos Chem, Beijing 100083, Peoples R China 2.Beijing Forestry Univ, MOE Key Lab Wooden Mat Sci & Applicat, Beijing 100083, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, Beijing 100090, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Jing,Chen, Pan,Yao, Wenjia,et al. Subcritical water extraction of betulinic acid from birch bark[J]. INDUSTRIAL CROPS AND PRODUCTS,2015,74(NOV):557-565. |
| APA | Liu, Jing.,Chen, Pan.,Yao, Wenjia.,Wang, Jia.,Wang, Luying.,...&Lei, Jiandu.(2015).Subcritical water extraction of betulinic acid from birch bark.INDUSTRIAL CROPS AND PRODUCTS,74(NOV),557-565. |
| MLA | Liu, Jing,et al."Subcritical water extraction of betulinic acid from birch bark".INDUSTRIAL CROPS AND PRODUCTS 74.NOV(2015):557-565. |
入库方式： OAI收割
来源：过程工程研究所
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