Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice
文献类型：期刊论文
| 作者 | Hu, Bingbing1,2; Dai, Fengying3; Fan, Zhanming4; Ma, Guanghui1; Tang, Qunwei2; Zhang, Xin1 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2015-10-07 |
| 卷号 | 27期号:37页码:5499-5505 |
| ISSN号 | 0935-9648 |
| 英文摘要 | As nanotheranostics, Congo red/Rutin-MNPs combine the abilities of diagnosis and treatment of Alzheimer's disease (AD). The biocompatible nanotheranostics system based on iron oxide magnetic nanoparticles, with ultrasmall size and excellent magnetic properties, can specifically detect amyloid plaques by magnetic resonance imaging, realize targeted delivery of AD therapeutic agents, achieve drug controlled release by H2O2 response, and prevent oxidative stress. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | SUPERPARAMAGNETIC IRON-OXIDE ; BLOOD-BRAIN-BARRIER ; MRI CONTRAST AGENTS ; A-BETA PLAQUES ; OXIDATIVE STRESS ; AMYLOID PLAQUES ; T-2 CONTRAST ; MOUSE-BRAIN ; NANOPARTICLES ; DELIVERY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000362727900005 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/19644]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Ocean Univ China, Inst Mat Sci & Engn, Qingdao 266100, Peoples R China 3.Beijing Ctr Phys & Chem Anal, Beijing 100084, Peoples R China 4.Capital Univ, Beijing Anzhen Hosp, Dept Radiol, Beijing 100029, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Bingbing,Dai, Fengying,Fan, Zhanming,et al. Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice[J]. ADVANCED MATERIALS,2015,27(37):5499-5505. |
| APA | Hu, Bingbing,Dai, Fengying,Fan, Zhanming,Ma, Guanghui,Tang, Qunwei,&Zhang, Xin.(2015).Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice.ADVANCED MATERIALS,27(37),5499-5505. |
| MLA | Hu, Bingbing,et al."Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice".ADVANCED MATERIALS 27.37(2015):5499-5505. |
入库方式： OAI收割
来源：过程工程研究所
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