Asymmetric Latent Carbocation Catalysis with Chiral Trityl Phosphate
文献类型：期刊论文
| 作者 | Lv, Jian1,2; Zhang, Qichao1; Zhong, Xingren1; Luo, Sanzhong1,2 |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
 |
| 出版日期 | 2015-12-16 |
| 卷号 | 137期号:49页码:15576-15583 |
| 英文摘要 | Stable carbocations such as tritylium ions have been widely explored as organic Lewis acid catalysts and reagents in organic synthesis. However, achieving asymmetric carbocation catalysis remains elusive ever since they were first identified over one century ago. The challenges mainly come from their limited compatibility, scarcity of chiral carbocations, as well as the extremely low barrier to racemization of chiral carbenium ions. We reported here a latent concept for asymmetric carbocation catalysis. In this strategy, chiral trityl phosphate is employed as the carbocation precursor, which undergoes facile ionic dissociation upon mild external stimulation (e.g., acid, H-bonding, polar substrates) to form a catalytically active chiral ion pair for substrate activation and chiral induction. The latent strategy provides a solution for the long sought-after asymmetric carbocation catalysis as illustrated in three different enantioselective transformations. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-02-25 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/29525]  |
| 专题 | 化学研究所_分子识别与功能实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China 2.Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lv, Jian,Zhang, Qichao,Zhong, Xingren,et al. Asymmetric Latent Carbocation Catalysis with Chiral Trityl Phosphate[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2015,137(49):15576-15583. |
| APA | Lv, Jian,Zhang, Qichao,Zhong, Xingren,&Luo, Sanzhong.(2015).Asymmetric Latent Carbocation Catalysis with Chiral Trityl Phosphate.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,137(49),15576-15583. |
| MLA | Lv, Jian,et al."Asymmetric Latent Carbocation Catalysis with Chiral Trityl Phosphate".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 137.49(2015):15576-15583. |
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来源：化学研究所
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