Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease
文献类型：期刊论文
| 作者 | He, Xiaofei1,2; Xing, Ronge1 ; Li, Kecheng1; Qin, Yukun1; Zou, Ping1,2; Liu, Song1; Yu, Huahua1; Li, Pengcheng1
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| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| 出版日期 | 2016 |
| 卷号 | 82期号:2016页码:614-620 |
| 关键词 | Degraded beta-chitosan Microwave-assisted Antiviral activities for Newcastle disease |
| 英文摘要 | Beta-chitosan has a parallel structure, which differs from alpha-chitosan's antiparallel structure while producing different properties and difficulties. In this paper, we prepared the beta-chitosan through acid and alkali methods and the resultant material was characterized by elemental analysis, FT-IR, HPLC, XRD, NMR and AFS. To increase the solubility and biological activity of the beta-chitosan, we degraded it through microwave-assisted process. After characterization, we determined that the chitosan had not changed its configuration during the reaction with H2O2 under microwave irradiation. The inhibitory activity of the degraded chitosan for Newcastle disease was revealed by a hemagglutination test and RT-PCR. The yield of the beta-chitosan was approximately 30%, and its molecular weight can be degraded to 1000 to 10,000 g/mol. Moreover, the degraded p-chitosan has higher antiviral activity, reducing the hemagglutination titre to zero, compared with alpha-chitosan. Therefore, beta-chitosan has good development prospects during the development of veterinary drugs for Newcastle disease. (c) 2015 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000367425100077 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/86656]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xiaofei,Xing, Ronge,Li, Kecheng,et al. Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,82(2016):614-620. |
| APA | He, Xiaofei.,Xing, Ronge.,Li, Kecheng.,Qin, Yukun.,Zou, Ping.,...&Li, Pengcheng.(2016).Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,82(2016),614-620. |
| MLA | He, Xiaofei,et al."Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 82.2016(2016):614-620. |
入库方式： OAI收割
来源：海洋研究所
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