Neolignans, lignans and glycoside from the fruits of Melia toosendan
文献类型：期刊论文
| 作者 | Wang, Lun ; Li, Fu ; Yang, Chun-Yan ; Khan, Ashfaq-Ahmad ; Liu, Xin ; Wang, Ming-Kui |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2014 |
| 卷号 | 99页码:92-98 |
| 关键词 | Melia toosendan Meliaceae Neolignans Lignans Glycoside Antioxidant activity |
| 产权排序 | 1 |
| 通讯作者 | Wang, MK (reprint author), Chinese Acad Sci, Chengdu Inst Biol, 9,Sect 4,Renmin South Rd, Chengdu 610041, Peoples R China. |
| 合作状况 | 其它 |
| 英文摘要 | Four new neolignans, meliasendanins A-D (1-4), and a new glycoside, toosenoside A (5), together with ten known ones (6-15), were isolated from a n-BuOH partition of the fruits of Melia toosendan. Their structures were elucidated by analyses of extensive spectroscopic data and comparison of the NMR data with those reported previously. Meliasendanin A (1) was a rare neolignan containing isochroman moiety, and its absolute configuration was determined using a CD spectrum. Toosenoside A (5) was an unusual glycoside with a rare naturally occurring aglycone and its structure was confirmed by X-ray single crystal diffraction analysis. The antioxidant activity of the isolated neolignans and lignans was evaluated by ABTS radical-scavenging assay. Compounds 1 and 13 exhibited strong antioxidant activity, with IC50 values of 62.8 and 45.1 mu M, respectively. (C) 2014 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry, Medicinal; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-02-26 |
| 源URL | [http://210.75.237.14/handle/351003/26658]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Wang, Lun,Li, Fu,Yang, Chun-Yan,et al. Neolignans, lignans and glycoside from the fruits of Melia toosendan[J]. FITOTERAPIA,2014,99:92-98. |
| APA | Wang, Lun,Li, Fu,Yang, Chun-Yan,Khan, Ashfaq-Ahmad,Liu, Xin,&Wang, Ming-Kui.(2014).Neolignans, lignans and glycoside from the fruits of Melia toosendan.FITOTERAPIA,99,92-98. |
| MLA | Wang, Lun,et al."Neolignans, lignans and glycoside from the fruits of Melia toosendan".FITOTERAPIA 99(2014):92-98. |
入库方式： OAI收割
来源：成都生物研究所
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