New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.
文献类型：期刊论文
| 作者 | Qin,Jing; Fan,Min ; He,Juan; Wu,Xing-De; Peng,Li-Yan; Su,Jia; Cheng,Xiao; Li,Yan; Kong,Ling-Mei; Li,Rong-Tao
|
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2015-09-17 |
| 卷号 | 29期号:18页码:1711-1718 |
| 关键词 | Morus alba L soroceal B sanggenol Q cytotoxic activity anti-inflammatory activity |
| 英文摘要 | Six Diels-Alder adducts (1-6) and nine prenylated flavanones (7-15) were isolated from the root bark of Morus alba L. Among them, soroceal B (1) and sanggenol Q (7) were new compounds. Their structures were elucidated on the basis of extensive spectroscopic methods, including 1D and 2D NMR techniques. Compounds 1-3, 9, 10, 12, 13 and 15 exhibited cytotoxic activity against five human tumour lines and compound 2 inhibited significantly selective cytotoxic activities towards HL-60 and AGS cells with IC50 of 3.4 and 3.6M. Compounds 3, 5, 9 and 12 exhibited moderate inhibitory activity against nitric oxide production in LPS-activated RAW264.7. |
| 类目[WOS] | Chemistry, Applied ; Chemistry, Medicinal |
| 研究领域[WOS] | Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | ALDER-TYPE ADDUCTS ; CULTIVATED MULBERRY TREE ; ROOT BARK ; CONSTITUENTS ; FLAVONOIDS ; ANTIOXIDANT ; FLAVANONES ; MONGOLICA ; KOIDZ ; LHOU |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000359849800004 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25102]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Qin,Jing,Fan,Min,He,Juan,et al. New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.[J]. NATURAL PRODUCT RESEARCH,2015,29(18):1711-1718. |
| APA | Qin,Jing.,Fan,Min.,He,Juan.,Wu,Xing-De.,Peng,Li-Yan.,...&Zhao,Qin-Shi.(2015).New cytotoxic and anti-inflammatory compounds isolated from Morus alba L..NATURAL PRODUCT RESEARCH,29(18),1711-1718. |
| MLA | Qin,Jing,et al."New cytotoxic and anti-inflammatory compounds isolated from Morus alba L.".NATURAL PRODUCT RESEARCH 29.18(2015):1711-1718. |
入库方式： OAI收割
来源：昆明植物研究所
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