Antibacterial monoterpenoid indole alkaloids from Alstonia scholaris cultivated in temperate zone
文献类型：期刊论文
| 作者 | Liu,Lu; Chen,Ying-Ying; Qin,Xu-Jie; Wang,Bei; Jin,Qiong; Liu,Ya-Ping; Luo,Xiao-Dong
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2015-09-01 |
| 卷号 | 105页码:160-164 |
| 关键词 | Alstonia scholaris Apocynaceae Monoterpenoid indole alkaloids Antibacterial activity |
| 英文摘要 | Three new monoterpenoid indole alkaloids, named normavacurine-21-one (1), 5-hydroxy-19, 20-E-alschomine (2), and 5-hydroxy-19, 20-Z-alschomine (3), together with thirteen known indole alkaloids (4-16) were isolated from the leaves of Alstonia scholaris cultivated in Kunming. Their structures were elucidated on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. The leaves of A. scholaris cultivated in Kunming, contained picrinine-type alkaloids, scholaricin-type alkaloids and nareline as major alkaloids. New compounds 1-3 might be derived from a common biogenetic precursor (5). Compounds 1,5 and 10 exhibited significant antibacterial activity against Enterococcus faecalis, and 3,9 and 14 against Pseudomonas aeruginosa with an MIC value of 0.781 mu g/mL, while 14 showed moderate activity against Klepsiella pneumonia with an MIC value of 1.56 mu g/mL. (C) 2015 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | FLIGHT MASS-SPECTROMETRY ; IN-VITRO ; LEAVES ; IDENTIFICATION ; CONSTITUENTS ; EXTRACT ; PLANT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361401500025 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25139]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu,Lu,Chen,Ying-Ying,Qin,Xu-Jie,et al. Antibacterial monoterpenoid indole alkaloids from Alstonia scholaris cultivated in temperate zone[J]. FITOTERAPIA,2015,105:160-164. |
| APA | Liu,Lu.,Chen,Ying-Ying.,Qin,Xu-Jie.,Wang,Bei.,Jin,Qiong.,...&Luo,Xiao-Dong.(2015).Antibacterial monoterpenoid indole alkaloids from Alstonia scholaris cultivated in temperate zone.FITOTERAPIA,105,160-164. |
| MLA | Liu,Lu,et al."Antibacterial monoterpenoid indole alkaloids from Alstonia scholaris cultivated in temperate zone".FITOTERAPIA 105(2015):160-164. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。