Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.
文献类型：期刊论文
| 作者 | Zhao,Qin; Wang,Gao-Qian; Chen,Guo-Dong; Hu,Dan; Li,Xiao-Xia; Guo,Liang-Dong; Li,Yan ; Yao,Xin-Sheng; Gao,Hao
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| 刊名 | STEROIDS
 |
| 出版日期 | 2015-10-01 |
| 卷号 | 102页码:101-109 |
| 关键词 | Xylariaceae Nodulisporium sp. Endolichenic fungus 4-Methyl-progesteroid derivatives |
| 英文摘要 | The fungus Nodulisporium sp. (No. 65-12-7-1), which can produce a rare class of steroids (4-methyl-progesteroids) in rice solid medium, was subjected to a one strain-many compounds (OSMAC) approach. It was found to produce ten new 4-methyl-progesteroid derivatives named nodulisporisteroids C-L (1-10) in potato-dextrose-broth (PDB) medium, which showed that the fungus was a prolific producer of 4-methyl-progesteroids. The structures of 1-10 were elucidated by spectroscopic and X-ray crystallographic analysis. Their cytotoxic activities against five human cancer cell lines had been evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. (C) 2015 Elsevier Inc. All rights reserved. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 关键词[WOS] | FUNGUS ; SESQUITERPENES ; METABOLITES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361251300014 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25144]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhao,Qin,Wang,Gao-Qian,Chen,Guo-Dong,et al. Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.[J]. STEROIDS,2015,102:101-109. |
| APA | Zhao,Qin.,Wang,Gao-Qian.,Chen,Guo-Dong.,Hu,Dan.,Li,Xiao-Xia.,...&Gao,Hao.(2015).Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp..STEROIDS,102,101-109. |
| MLA | Zhao,Qin,et al."Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.".STEROIDS 102(2015):101-109. |
入库方式： OAI收割
来源：昆明植物研究所
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