Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013
文献类型：期刊论文
| 作者 | Li,Jing ; Xie,Jin; Yang,Yin-He; Li,Xiao-Lian; Zeng,Ying; Zhao,Pei-Ji
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2015-09-01 |
| 卷号 | 81期号:14页码:1285-1289 |
| 关键词 | Pestalotiopsis sp cr013 Amphisphaeriaceae pestalpolyol X-ray crystallography polyketide cytotoxic activity |
| 英文摘要 | Four novel polyketides, named pestalpolyols A (1), B (2), C (3), and D (4), were isolated from solid fermentation products of Pestalotiopsis sp. cr013. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2Dnuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry experiments, and the absolute configuration was confirmed by single-crystal X-ray diffraction analysis using the anomalous scattering of Cu K radiation. The inhibitory activities of compounds 1, 2, and 4 against five human tumor lines were tested in vitro, and showed IC50 values 2.3-31.2 mu M. |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | MICROSPORA ; METABOLITE ; HAWAII ; ACID |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361681000008 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25150]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Li,Jing,Xie,Jin,Yang,Yin-He,et al. Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013[J]. PLANTA MEDICA,2015,81(14):1285-1289. |
| APA | Li,Jing,Xie,Jin,Yang,Yin-He,Li,Xiao-Lian,Zeng,Ying,&Zhao,Pei-Ji.(2015).Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013.PLANTA MEDICA,81(14),1285-1289. |
| MLA | Li,Jing,et al."Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013".PLANTA MEDICA 81.14(2015):1285-1289. |
入库方式： OAI收割
来源：昆明植物研究所
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