Four new fawcettimine-related alkaloids from Phlegmariurus squarrosus
文献类型：期刊论文
| 作者 | Liu,Yu-Chen; Fan,Min ; Jiang,Wei-Wei; Liu,Fei; Wu,Xing-De; He,Juan; Cheng,Xiao; Peng,Li-Yan; Su,Jia; Zhang,Zhi-Jun
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| 出版日期 | 2015-10-03 |
| 卷号 | 17期号:10页码:967-975 |
| 关键词 | fawcettimine-related alkaloids Phlegmariurus squarrosus BACE1 inhibitory activity AChE inhibitory activity |
| 英文摘要 | Four new fawcettimine-related alkaloids (1-4), together with 17 known ones, were isolated from club moss Phlegmariurus squarrosus. Notably, compound 1 was the derivative of lycoflexine with an unprecedented additional methyl group at C-17. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, and HR-MS, as well as by comparison with the literature data. All new compounds were tested for their -site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) and acetylcholinesterase (AChE) inhibitory activities. |
| 类目[WOS] | Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | LYCOPODIUM ALKALOIDS ; HUPERZINE-B |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000363659800002 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25227]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu,Yu-Chen,Fan,Min,Jiang,Wei-Wei,et al. Four new fawcettimine-related alkaloids from Phlegmariurus squarrosus[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2015,17(10):967-975. |
| APA | Liu,Yu-Chen.,Fan,Min.,Jiang,Wei-Wei.,Liu,Fei.,Wu,Xing-De.,...&Zhao,Qin-Shi.(2015).Four new fawcettimine-related alkaloids from Phlegmariurus squarrosus.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,17(10),967-975. |
| MLA | Liu,Yu-Chen,et al."Four new fawcettimine-related alkaloids from Phlegmariurus squarrosus".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 17.10(2015):967-975. |
入库方式： OAI收割
来源：昆明植物研究所
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