Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis
文献类型：期刊论文
| 作者 | Qin,Xu-Jie; Yu,Mu-Yuan; Ni,Wei; Yan,Huan; Chen,Chang-Xiang; Cheng,Yung-Chi; He,Li; Liu,Hai-Yang
|
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 121页码:20-29 |
| 关键词 | Paris polyphylla var. yunnanensis Trilliaceae Steroidal saponins Chonglouosides SL-9-SL-20 Cytotoxicity Anti-HCV activity |
| 英文摘要 | Phytochemical investigation of the stems and leaves of Paris polyphyila var. yunnanensis led to isolation of 12 steroidal saponins, chonglouosides SL-9-SL-20, which had not been described previously, along with 13 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Four of the twelve steroidal saponins possessed three steroidal aglycones which have not been reported in nature. Steroidal saponins were also evaluated for their cytotoxicities against two human cancer cell lines (HepG2 and HEK293) and anti-HCV effects. One known steroidal saponin was the most cytotoxic compound overall with IC50 values of 2.9 +/- 0.5 mu M and 5.0 +/- 0.6 mu M against HepG2 and HEK293 cell lines, respectively, while none showed anti-HCV activity at a concentration of 20 mu M. (C) 2015 Elsevier Ltd. All rights reserved. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | STRUCTURAL REQUIREMENT ; SPIROSTANE GLYCOSIDES ; FRUITS ; FLOWERS ; AGENTS ; MODE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000366445300003 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25262]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Qin,Xu-Jie,Yu,Mu-Yuan,Ni,Wei,et al. Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis[J]. PHYTOCHEMISTRY,2016,121:20-29. |
| APA | Qin,Xu-Jie.,Yu,Mu-Yuan.,Ni,Wei.,Yan,Huan.,Chen,Chang-Xiang.,...&Liu,Hai-Yang.(2016).Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis.PHYTOCHEMISTRY,121,20-29. |
| MLA | Qin,Xu-Jie,et al."Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis".PHYTOCHEMISTRY 121(2016):20-29. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。