Alkaloids with Different Carbon Units from Myrioneuron faberi
文献类型：期刊论文
| 作者 | Cao,Ming-Ming; Zhang,Yu ; Huang,Sheng-Dian; Di,Ying-Tong; Peng,Zong-Gen; Jiang,Jian-Dong; Yuan,Chun-Mao; Chen,Duo-Zhi; Li,Shun-Lin; He,Hong-Ping
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2015-11-01 |
| 卷号 | 78期号:11页码:2609-2616 |
| 英文摘要 | Three new Myrioneuron alkaloids, myrifamines A-C (1-3), with unique skeletons were isolated from Myrioneuron faberi. The absolute configuration of 1 was confirmed by single-crystal X-ray diffraction analysis, and the stereochemistry of the other two alkaloids was determined using a combination of ROESY experiments and calculated and experimental electronic circular dichroism spectra. Myrifamine C (3) is the first example of a symmetric dimer among the Myrioneuron alkaloids. Known alkaloids myrionamide (4) and schoberine (5) were also isolated, and experimental NMR and X-ray diffraction data suggest their structural revision. Compound 2 showed significant inhibitory activity toward the hepatitis C virus in vitro, with a therapeutic index (CC50/EC50) greater than 108.7. |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | NUTANS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000366005800013 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25266]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Cao,Ming-Ming,Zhang,Yu,Huang,Sheng-Dian,et al. Alkaloids with Different Carbon Units from Myrioneuron faberi[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(11):2609-2616. |
| APA | Cao,Ming-Ming.,Zhang,Yu.,Huang,Sheng-Dian.,Di,Ying-Tong.,Peng,Zong-Gen.,...&Hao,Xiao-Jiang.(2015).Alkaloids with Different Carbon Units from Myrioneuron faberi.JOURNAL OF NATURAL PRODUCTS,78(11),2609-2616. |
| MLA | Cao,Ming-Ming,et al."Alkaloids with Different Carbon Units from Myrioneuron faberi".JOURNAL OF NATURAL PRODUCTS 78.11(2015):2609-2616. |
入库方式： OAI收割
来源：昆明植物研究所
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