中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway

文献类型:期刊论文

作者Chen, Xiao-Qiang; Zhao, Si-Meng; Wang, Zhe; Zeng, Guang-Zhi; Huang, Mao-Bo; Tan, Ning-Hua
刊名TETRAHEDRON
出版日期2015-12-30
卷号71期号:52页码:9673-9678
关键词Rubia cordifolia Rubicordins A-C Cyclopeptides Cytotoxicity NF-kappa B signaling pathway
英文摘要Three new cyclic hexapeptides, named as rubicordins A-C (1-3), together with seven known ones (4-10) were isolated from the roots and rhizomes of Rubia cordifolia. Their structures were elucidated by spectroscopic analysis, and the cytotoxic and NF-kappa B signaling pathway activities were tested. The results indicated that 1-10 showed cytotoxicity against SGC-7901, A549 or Hela cancer cell lines, and 1-3 inhibited NF-kappa B signaling pathway. (C) 2015 Elsevier Ltd. All rights reserved.
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]ANTITUMOR CYCLIC HEXAPEPTIDES ; BREAST-CANCER CELLS ; RA-V ; ABSOLUTE-CONFIGURATION ; PLANT CYCLOPEPTIDES ; MARFEYS METHOD ; RUBIYUNNANINS ; YUNNANENSIS ; APOPTOSIS ; RADIX
收录类别SCI
语种英语
WOS记录号WOS:000366535800012
源URL[http://ir.kib.ac.cn/handle/151853/25321]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式
GB/T 7714
Chen, Xiao-Qiang,Zhao, Si-Meng,Wang, Zhe,et al. Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway[J]. TETRAHEDRON,2015,71(52):9673-9678.
APA Chen, Xiao-Qiang,Zhao, Si-Meng,Wang, Zhe,Zeng, Guang-Zhi,Huang, Mao-Bo,&Tan, Ning-Hua.(2015).Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway.TETRAHEDRON,71(52),9673-9678.
MLA Chen, Xiao-Qiang,et al."Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway".TETRAHEDRON 71.52(2015):9673-9678.

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来源:昆明植物研究所

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